Relationships among Substance Use, Sociodemographics, Pre-Exposure Prophylaxis (PrEP) Awareness and Related Attitudes among Young Adult Men Who Have Sex with Men.

Relationships among Substance Use, Sociodemographics, Pre-Exposure Prophylaxis (PrEP) Awareness and Related Attitudes among Young Adult Men Who Have Sex with Men.
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DOI:
10.1080/10826084.2022.2040030
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发表时间:
2022
影响因子:
2
通讯作者:
Leeman, Robert F.
Leeman, Robert F.
中科院分区:
医学4区
文献类型:
--
作者:
Gebru, Nioud Mulugeta;Benvenuti, Maria Costanza;Rowland, Bonnie H. P.;Kalkat, Meher;Chauca, Patricia G.;Leeman, Robert F.

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男男性行为者 (MSM) 占新艾滋病毒诊断人数的三分之二。暴露前预防(PrEP)是一种高效的艾滋病毒预防药物,但尚未得到充分利用。确定 PrEP 意识和态度的相关性可能有助于增加 PrEP 的使用。因此,我们评估了 (1) PrEP 意识; (2) 对药物使用和社会人口统计的认识存在差异; (3) 初始 PrEP 信息来源; (4) 信息来源和 PrEP 相关态度之间可能存在的关联。来自美国南部的年轻成人(18-30 岁)HIV 阴性 MSM 进行了一项网络调查,包括有关药物使用、性行为、感知的 HIV 风险和 PrEP 的问题。 2018 年 1 月至 2020 年 1 月期间,通过现场和在线方式招募参与者。在 506 名参与者中,89% 的人了解 PrEP。饮酒量高且感知艾滋病毒风险较高的参与者不了解 PrEP 的几率较高,且有少数种族/族裔的趋势。了解 PrEP 的参与者报告称,总体安全性较高,对 PrEP 功效有信心,并且认为坚持的难度较低,尽管那些具有较高 HIV 风险的参与者和吸烟者的态度较差。大多数参与者第一次听说 PrEP 是通过互联网。初始信息来源中与 PrEP 相关的态度没有统计学上的显着差异。物质使用与种族/族裔少数群体状况之间的关联以及缺乏 PrEP 意识表明了教育活动的优先亚组。未来的活动可能会根据各自的受众定制外展材料(例如,为西班牙裔人提供西班牙语材料),并在使用药物的个人更有可能看到的地方(例如酒类和便利店)进行传播。
Men who have sex with men (MSM) account for two-thirds of new HIV diagnoses. Pre-exposure prophylaxis (PrEP), a highly efficacious HIV preventive medication, is underutilized. Identifying correlates of PrEP awareness and attitudes may help increase PrEP use. Thus, we evaluated (1) PrEP awareness; (2) differences in awareness related to substance use and sociodemographics; (3) initial PrEP information sources; and (4) possible associations between information sources and PrEP-related attitudes. Young adult (ages 18–30) HIV-negative MSM from Southern U.S. undertook a web survey including questions about substance use, sexual behaviors, perceived HIV risk, and PrEP. Participants were recruited using in-person and online approaches between January 2018 - January 2020. Of 506 participants, 89% were aware of PrEP. Participants with high alcohol consumption and greater perceived HIV risk had higher odds of PrEP unawareness with a trend for minority race/ethnicity. PrEP-aware participants reported high overall perceived safety, confidence in PrEP’s efficacy, and low perceived difficulties with adherence though those with higher perceived HIV risk and individuals who used tobacco had less favorable attitudes. Most participants first heard about PrEP from the internet. There were no statistically significant differences in PrEP-related attitudes across initial information sources. Associations between substance use and racial/ethnic minority status and lack of PrEP awareness suggest priority subgroups for educational campaigns. Future campaigns may tailor outreach materials to the respective audience (e.g., Spanish materials for Hispanic people) and disseminate where individuals who use substances may be more likely to see them (e.g., liquor and convenience stores).
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