The significance of noncondylomatous wart virus infection of the cervical transformation zone. A review with discussion of two illustrative cases.
The significance of noncondylomatous wart virus infection of the cervical transformation zone. A review with discussion of two illustrative cases.
复制标题
宫颈转化区非尖锐湿疣病毒感染的意义。
作者：
C. Laverty;P. Russell;E. Hills;N. Booth
临床病理特征描述的两个病人的宫颈细胞学涂片显示的功能，最初被认为是表明发育不良，但后来被认为是尖锐湿疣。一名患者是免疫抑制肾移植受者，另一名是常规妇科门诊患者。没有尖锐湿疣是可识别的临床，阴道镜检查显示只有一个平坦的，但不典型的转化区。每例活组织检查均显示非湿疣性疣状病变，电子显微镜下可见疣病毒颗粒。这些病例突出了宫颈转化区疣病毒感染所遇到的临床、阴道镜、细胞学和组织学诊断困难，这些困难比以前认识到的要普遍。疣病毒感染的宫颈癌的可能关系也进行了讨论。
The clinicopathologic features are described of two patients whose cervical cytology smears showed features which were thought initially to indicate dysplasia, but which were later considered to be those of condylomata acuminata. One patient was an immunosuppressed renal transplant recipient, the other was a routine gynecologic clinic patient. No condylomas were recognizable clinically, and colposcopy showed only a flat but atypical transformation zone. Biopsy in each case showed a noncondylomatous warty lesion and wart virus particles were demonstrated by electron microscopy. These cases highlight the clinical, colposcopic, cytologic and histologic diagnostic difficulties which are encountered with cervical transformation zone wart virus infections, which are commoner than formerly realized. The possible relationship of wart virus infection to cancer of the cervix is also discussed.