Potential of diffusion-weighted imaging in magnetic resonance enterography to identify neoplasms in the ileocecal region: Use of ultra-high b-value diffusion-weighted imaging
Potential of diffusion-weighted imaging in magnetic resonance enterography to identify neoplasms in the ileocecal region: Use of ultra-high b-value diffusion-weighted imaging
复制标题
磁共振肠造影中弥散加权成像识别回盲部肿瘤的潜力：超高 b 值弥散加权成像的使用。
DOI：
10.3892/ol.2019.10441
复制
发表时间：
2019-08-01
期刊：
影响因子：
2.9
通讯作者：
Hu, Daoyu
中科院分区：
文献类型：
--
作者：
Yu, Hao;Feng, Cui;Hu, Daoyu
慢性炎症性肠病患者患结直肠癌的风险增加，肿瘤性病变和炎症性病变之间的鉴别常常造成临床困境。本研究的目的是探讨超高b值的弥散加权（DW）磁共振（MR）小肠造影是否有助于识别回盲部肿瘤性病变。从292例疑似肠道疾病病例中共纳入76例患者（22例肿瘤患者，26例炎性病变患者和28例正常受试者）。所有患者均在3 T MR扫描仪上进行常规MR小肠造影和DW成像（DWI），其中7种不同的b值（400，600，800，1，000，1，200，1，500和3，000 sec/mm 2）。由两名放射科医生独立分析不同b值的DWI扫描是否存在回盲部病变。随着b值的增加，大多数炎性病变和正常肠段的信号强度逐渐降低至背景强度;然而，肿瘤性病变显示出与背景相比的相对高信号。此外，B= 3，000 sec/mm 2 DWI的阳性结果中约76%为肿瘤。总之，DWI图像中具有持续高信号强度且b值增加至3，000 sec/mm 2的病变表明存在肿瘤。结果表明，超高b值（3，000 sec/mm 2）成像可能有助于肿瘤与良性疾病的临床鉴别。
Patients with chronic inflammatory bowel disease have an increased risk of colorectal cancer, and the differentiation between neoplastic and inflammatory lesions often poses a clinical dilemma. The aim of the present study was to investigate whether diffusion-weighted (DW) magnetic resonance (MR) enterography with ultra-high b-value facilitates the identification of neoplastic lesions in the ileocecal region. A total of 76 patients (22 patients with neoplasms, 26 inflammatory lesions and 28 normal subjects) from 292 cases of suspected bowel disorders were included in the present study. All patients were examined with conventional MR enterography and DW imaging (DWI) with seven different b-values (400, 600, 800, 1,000, 1,200, 1,500 and 3,000 sec/mm2) in a 3T MR scanner. DWI scans with different b-values were analyzed independently by two radiologists for the presence of ileocecal lesions. The signal intensity of the majority of inflammatory lesions and normal bowel segments gradually decreased to the background intensity with increasing b-values; however, neoplastic lesions demonstrated relative hyperintensity compared with the background. In addition, ~76% of the positive findings from b=3,000 sec/mm2 DWI were neoplasms. In conclusion, a lesion with consistently high signal intensity from DWI images with b-values increasing to 3,000 sec/mm2 indicated the presence of neoplasms. The results suggested that ultra-high b-value (3,000 sec/mm2) imaging may aid the clinical differentiation of neoplasms from benign conditions.