Comparable studies of the incidence of stroke and its pathological types - Results from am international collaboration
Comparable studies of the incidence of stroke and its pathological types - Results from am international collaboration
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DOI：
10.1161/01.str.28.3.491
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发表时间：
1997-03-01
期刊：
影响因子：
8.3
通讯作者：
Warlow, CP
中科院分区：
文献类型：
--
作者：
Sudlow, CLM;Warlow, CP
背景和目的比较世界不同地区的卒中发病率可以增加我们对病因和预防的理解。然而，只有当研究使用标准的定义和方法，并提供完整的数据时，比较才有意义。我们比较了脑卒中的发病率及其病理类型方法1984年年中或以后的研究，满足可比较的，以社区为基础的研究的标准标准，提供原始数据进行比较分析。结果到1995年年中，数据来自欧洲，俄罗斯，澳大拉西亚和美国，包括约350万人年和5575例中风事件。在大多数地区，45 - 84岁受试者的年龄和性别标准化年发病率相似（约在300/100 000和500/100 000之间），但法国第戎戎（238/100 000）显著较低，俄罗斯新西伯利亚（627/100 000）较高。然而，在75至84岁的受试者中，新西伯利亚的排名不再高于其他研究。病理类型的分布，当这些是可靠的区分，并没有显着差异studies.Conclusions中风发病率和病理类型的相似性，也许并不令人惊讶，因为所有的人群都西化，主要是白色。新西伯利亚的高发病率在老年人中消失，而第戎戎的低发病率有几种可能的解释。这些因素包括方法上的人为因素和不同的人群风险因素模式。需要进一步的工作来探索这些可能性，并将我们对中风发病率的了解扩展到世界其他地区，特别是发展中国家。
Background and Purpose Comparing stroke rates in different parts of the world may increase our understanding of both etiology and prevention. However, comparisons are meaningful only if studies use standard definitions and methods, with comparably presented data. We compared the incidence of stroke and its pathological types (cerebral infarction, primary intracerebral hemorrhage, and subarachnoid hemorrhage) in recent studies from around the world.Methods Studies with a midyear of 1984 or later, fulfilling standard criteria for a comparable, community-based study, provided original data for comparative analyses.Results By mid-1995, data were available from 11 studies in Europe, Russia, Australasia, and the United States, comprising approximately 3.5 million person-years and 5575 incident strokes. Age- and sex-standardized annual incidence rates for subjects aged 45 to 84 years were similar (between approximately 300/100 000) and 500/100 000) in most places but were significantly lower in Dijon, France (238/100 000), and higher in Novosibirsk, Russia (627/100 000). In subjects aged 75 to 84 years, however, Novosibirsk no longer ranked higher than the other studies. The distribution of pathological types, when these were reliably distinguished, did not differ significantly between studies.Conclusions The similarities in stroke incidence and pathological types are perhaps not surprising given that all the populations were westernized and mainly white. The higher rates in Novosibirsk, disappearing in the elderly, and the lower rates in Dijon have several potential explanations. These include methodological artifact and different patterns of population risk factors. Further work is needed to explore these possibilities and to extend our knowledge of stroke incidence to other parts of the world, especially developing countries.