ENVIRONMENTAL-FACTORS IN DEPRESSIVE-ILLNESS
ENVIRONMENTAL-FACTORS IN DEPRESSIVE-ILLNESS
复制标题
DOI：
10.1192/bjp.111.472.243
复制
发表时间：
1965-01-01
影响因子：
10.5
通讯作者：
PRIEST, RG
中科院分区：
文献类型：
--
作者：
FORREST, AD;FRASER, RH;PRIEST, RG
158例患者和58名对照组在内科病房治疗进行了研究，他们的经验，某些社会和医疗因素在3年前入院或转诊。两组儿童的父母丧亲经历也进行了研究。抑郁症患者在入院或转诊前3年内经历了更多的童年丧亲（显著），更多的社会因素（显著），更多的医疗或身体疾病因素（不显著）。105例患者的泌尿学数据记录在一份泌尿系统症状清单上。根据对5种症状中的4种（迟缓、昼夜变化、清晨觉醒、注意力受损和内疚感）的评分，将患者归类为“内源性”，而将其余患者归类为“神经质”。然后比较这些组的疾病严重程度、60岁以上的发病率、入院前社会和医疗压力因素的发病率以及躁狂抑郁症的发病率。“内源性”组包括所有躁狂抑郁症患者和大多数重症患者。其他因素并没有区分各组。这些研究结果被讨论的概念，抑郁症作为有一些生物学的目的，在某种程度上保护或消除有害或紧张的生活情况的主题。
One hundred and fifty-eight patients and 58 control subjects under treatment in medical wards were studied in regard to their experience of certain social and medical factors in the 3 years prior to admission or referral. The childhood experience of parental bereavement in both groups was also studied. The depressive patients had experienced more childhood bereavement (significant), more social factors (significant), and more medical or physical illness factors (not significant) in the 3 years prior to admission or referral. Data on symptomatology had been recorded on a symptom-sign inventory for 105 patients. On the basis of scoring on 4 out of 5 symptoms (retardation, diurnal variation, early morning wakening, impaired concentration, and ideas of guilt) patients were classified as "endogenous", while the rest were classified as "neurotic". These groups were then compared for severity of illness, incidence of age over 60 years, incidence of pre-admission social and medical stress factors, and incidence of manic-depressive illness. The "endogenous" group had all the manic-depressive patients and the majority of severely ill patients. Other factors did not discriminate between the groups. These findings were discussed in relation to the concept of depressive illness as having some biological purpose as in some way protecting or removing the subject from a noxious or stressful life situation.