Scipion: A software framework toward integration, reproducibility and validation in 3D electron microscopy

Scipion: A software framework toward integration, reproducibility and validation in 3D electron microscopy
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DOI:
10.1016/j.jsb.2016.04.010
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发表时间:
2016-07-01
影响因子:
3
通讯作者:
Carazo, J. M.
Carazo, J. M.
中科院分区:
生物学3区
文献类型:
--
作者:
de la Rosa-Trevin, J. M.;Quintana, A.;Carazo, J. M.

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在过去的几年里,三维电子显微镜(3DEM)经历了仪器和方法的革命。在这场影响广泛的变革中,核心角色之一是图像处理软件的不断发展。在这里,我们提出了Scipion,通过基于工作流的方法集成几个3DEM软件包的软件框架。Scipion允许执行可重复使用,标准化,可追溯和可再现的图像处理协议。这些协议整合了来自不同程序的工具,同时提供了它们之间的完全互操作性。Scipion是一个开源项目,可以从http://scipion.cnb.csic.es下载。(C)2016 Elsevier Inc. All rights reserved.
In the past few years, 3D electron microscopy (3DEM) has undergone a revolution in instrumentation and methodology. One of the central players in this wide-reaching change is the continuous development of image processing software. Here we present Scipion, a software framework for integrating several 3DEM software packages through a workflow-based approach. Scipion allows the execution of reusable, standardized, traceable and reproducible image-processing protocols. These protocols incorporate tools from different programs while providing full interoperability among them. Scipion is an open-source project that can be downloaded from http://scipion.cnb.csic.es. (C) 2016 Elsevier Inc. All rights reserved.