Plant responses to extracellular nucleotides: Cellular processes and biological effects.
Plant responses to extracellular nucleotides: Cellular processes and biological effects.
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DOI：
10.1007/s11302-005-3981-6
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发表时间：
2006-09
影响因子：
3.5
通讯作者：
Roux, Stanley J
中科院分区：
文献类型：
--
作者：
Jeter, Collene R;Roux, Stanley J
高等植物对外源嘌呤核苷酸的应用表现出细胞反应，其方式与这些分子的细胞间信号传导功能一致。与动物一样，植物通过增加细胞质钙浓度来响应细胞外 ATP、ADP 和稳定类似物（例如 ATPγS 和 ADPβS）。激动剂底物特异性和浓度依赖性表明受体介导这些事件，并且，尽管植物受体的身份目前未知，但药理学分析指出质膜定位钙通道的参与。细胞外 ATP 还可以诱导活性氧的产生，并刺激许多胁迫和钙调节基因 mRNA 水平的增加，这表明基于核苷酸的信号传导在植物伤口和防御反应中发挥作用。此外，植物的生长和发育也可以通过施加外部 ATP 来改变。最近的研究才刚刚开始揭示响应细胞外 ATP 激活的植物信号网络的复杂性，以及它们如何相互作用以影响植物的生理过程。
Higher plants exhibit cellular responsiveness to the exogenous application of purine nucleotides in a manner consistent with a cell–cell signaling function for these molecules. Like animals, plants respond to extracellular ATP, ADP, and stable analogues (e.g., ATPγS and ADPβS) by increasing the cytoplasmic concentration of calcium. Agonist substrate specificity and concentration dependency suggest receptor mediation of these events, and, although the identity of the plant receptor is currently unknown, pharmacological analysis points to the involvement of a plasma membrane-localized calcium channel. Extracellular ATP can also induce the production of reactive oxygen species and stimulate an increase in the mRNA levels of a number of stress- and calcium-regulated genes, suggesting a role for nucleotide-based signaling in plant wound and defense responses. Furthermore, the growth and development of plants can also be altered by the application of external ATP. Recent studies are only beginning to uncover the complexities of plant signaling networks activated in response to extracellular ATP and how these might interact to affect plant physiological processes.