Highly sensitive voltammetric sensor based on NiO nanoparticle room temperature ionic liquid modified carbon paste electrode for levodopa analysis
Highly sensitive voltammetric sensor based on NiO nanoparticle room temperature ionic liquid modified carbon paste electrode for levodopa analysis
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DOI：
10.1016/j.molliq.2015.04.023
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发表时间：
2015-08
影响因子：
6
通讯作者：
M. Fouladgar;H. Karimi-Maleh;V. Gupta
中科院分区：
文献类型：
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作者：
M. Fouladgar;H. Karimi-Maleh;V. Gupta
本文研究了氯化1-甲基-3-丁基咪唑离子液体-NiO纳米粒子修饰碳糊电极（MBICl/NiO/NPs/CPE）用于真实的样品中左旋多巴（l-DOPA）的伏安测定。我们描述了NiO/NPs的合成和表征与不同的方法，如透射电子显微镜（TEM），能量色散X射线光谱（EDS）和X射线衍射（XRD）。DOPA的电化学氧化过程为pH依赖的2 e-和2 H+过程，电极反应遵循扩散控制的途径。LDOPA在MBICl/NiO/NPs/CPE上的氧化峰电位为450 mV，比在传统碳糊电极（CPE）上的氧化峰电位降低了约90 mV，氧化峰电流提高了约3.0倍。计算了其电化学参数如电荷转移系数（α = 0.73）。采用微分脉冲伏安法（DPV），线性响应范围为0.7-900 μmol L-1，检出限为0.4 μmol L-1。实验结果表明，该传感器具有选择性高、灵敏度高、响应速度快等特点。
This paper describes the development of 1-methyl-3-butylimidazolium chloride ionic liquid-NiO nanoparticle modified carbon paste electrode (MBICl/NiO/NPs/CPE) for the voltammetric determination of levodopa (l-DOPA) in real samples. We describe the synthesis and characterization of NiO/NPs with different methods such as transmission electron microscopy (TEM); energy-dispersive X-ray spectroscopy (EDS) and X-ray diffraction (XRD). The electrochemical oxidation ofl-DOPA occurred in a pH-dependent 2e−and 2H+process, and the electrode reaction followed a diffusion-controlled pathway. The oxidation peak potential of LDOPA on the MBICl/NiO/NPs/CPE appeared at 450 mV, which was about 90 mV decrease of the overpotential compared to that obtained on the traditional carbon paste electrode (CPE) and the oxidation peak current was increased for about 3.0 times. The electrochemical parameter such as charge transfer coefficient (α = 0.73) was calculated. The linear response range and detection limit were found to be 0.7–900 μmol L− 1and 0.4 μmol L− 1, respectively using the differential pulse voltammetry method (DPV). The results showed that the proposed sensor is highly selective, sensitive with a fast response forl-DOPA analysis.