Facile Synthesis of the Dicyanophosphide Anion via Electrochemical Activation of White Phosphorus: An Avenue to Organophosphorus Compounds
Facile Synthesis of the Dicyanophosphide Anion via Electrochemical Activation of White Phosphorus: An Avenue to Organophosphorus Compounds
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DOI：
10.1021/jacs.1c11087
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发表时间：
2022-01-18
影响因子：
15
通讯作者：
Liu, Liu Leo
中科院分区：
文献类型：
--
作者：
Mei, Yanbo;Yan, Zeen;Liu, Liu Leo
有机磷化合物（Organophosphorus compounds，OPCs）由于其在合成化学、材料科学和生物科学等领域的广泛应用，在过去的几十年里引起了人们极大的兴趣。本文描述了一种通过关键的桥连阴离子[P（CN）（2）]（-）将白色磷（P-4）转化为具有高P原子经济性的有用OPC的实用和通用的方法。这种阴离子可以通过电化学过程直接从P-4以克级制备。涉及膦酰亚胺、环磷烷和磷脂的各种OPC已经以两步的方式从P-4容易地获得。我们的方法对未来在实验室和工业环境中制备OPC具有重大影响。
Organophosphorus compounds (OPCs) have gained tremendous interest in the past decades due to their wide applications ranging from synthetic chemistry to materials and biological sciences. We describe herein a practical and versatile approach for the transformation of white phosphorus (P-4) into useful OPCs with high P atom economy via a key bridging anion [P(CN)(2)](-). This anion can be prepared on a gram scale directly from P-4 through an electrochemical process. A variety of OPCs involving phosphinidenes, cyclophosphanes, and phospholides have been made readily accessible from P-4 in a two-step manner. Our approach has a significant impact on the future preparation of OPCs in laboratory and industrial settings.