The contribution of prefrontal cortex to global perception
The contribution of prefrontal cortex to global perception
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DOI：
10.1007/s00221-007-0939-7
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发表时间：
2007-08-01
影响因子：
2
通讯作者：
Ladavas, Elisabetta
中科院分区：
文献类型：
--
作者：
Ciaramelli, Elisa;Leo, Fabrizio;Ladavas, Elisabetta
最近的研究表明，自上而下的调节信号在知觉加工中起着重要的作用，特别是在局部基本信息整合形成全局整体知觉的过程中。在这项研究中，我们调查了前额皮质是否可能在人类的这种自上而下的调节中起作用。我们测量了6名前额叶病变患者、4名颞叶病变对照患者和17名健康对照患者对由光栅斑块闭合链定义的圆的感知阈值。当模式稀疏时，前额叶病变患者的表现比颞叶病变患者和正常对照组差，需要在相对广泛的空间区域进行整合，但在更密集的模式上与对照组相似。结果清楚地表明，当元素没有形成“弹出”显示时，前额叶皮层在将基本特征整合为整体感知的过程中。
Recent research suggests a role of top-down modulatory signals on perceptual processing, particularly for the integration of local elementary information to form a global holistic percept. In this study we investigated whether prefrontal cortex may be instrumental in this top-down modulation in humans. We measured detection thresholds for perceiving a circle defined by a closed chain of grating patches in 6 patients with prefrontal lesions, 4 control patients with temporal lesions and 17 healthy control subjects. Performance of patients with prefrontal lesions was worse than that of patients with temporal lesions and normal controls when the patterns were sparse, requiring integration across relatively extensive regions of space, but similar to the control groups for denser patterns. The results clearly implicate the prefrontal cortex in the process of integrating elementary features into a holistic global percept, when the elements do not form a "pop-out" display.