THE RELATIONSHIP BETWEEN MALE CIRCUMCISION AND HIV INFECTION IN AFRICAN POPULATIONS
THE RELATIONSHIP BETWEEN MALE CIRCUMCISION AND HIV INFECTION IN AFRICAN POPULATIONS
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DOI：
10.1097/00002030-198906000-00006
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发表时间：
1989-06-01
期刊：
影响因子：
3.8
通讯作者：
CONANT, F
中科院分区：
文献类型：
--
作者：
BONGAARTS, J;REINING, P;CONANT, F
艾滋病毒血清阳性率和未包皮环切的男性在非洲国家的比例之间的关系进行检查，以确定包皮环切术的做法是否发挥作用，解释非洲艾滋病毒流行的规模现有的巨大变化。对人类学文献的审查得出了409个非洲族裔群体的包皮环切习俗估计数，并据此得出了相应的国家估计数。首都城市的艾滋病毒血清阳性率被用作各国艾滋病毒感染相对水平的指标。在37个非洲国家，这两个变量之间的相关性很高（R = 0.9; P < 0.001）。这一发现与现有的基于临床的研究一致，这些研究表明包皮环切术男性感染艾滋病毒的风险较低。
The relationship between HIV seroprevalence and the proportion of uncircumcised males in African countries is examined to determine whether circumcision practices play a role in explaining the large existing variation in the sizes of African HIV epidemics. A review of the anthropological literature yielded estimates of circumcision practices for 409 African ethnic groups from which corresponding national estimates were derived. HIV seroprevalence rates in the capital cities were used as indicators of the relative level of HIV infection of countries. The correlation between these two variables in 37 African countries was high (R = 0.9; P < 0.001). This finding is consistent with existing clinic-based studies that indicate a lower risk of HIV infection among circumcised males.