Filamentous bacterial viruses. XI. Molecular architecture of the class II (Pf1, Xf) virion.
Filamentous bacterial viruses. XI. Molecular architecture of the class II (Pf1, Xf) virion.
复制标题
丝状细菌病毒。
DOI：
10.1016/0022-2836(74)90336-2
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发表时间：
1974
影响因子：
5.6
通讯作者：
E. Wachtel
中科院分区：
文献类型：
--
作者：
D. Marvin;R. Wiseman;E. Wachtel
丝状细菌病毒（II类）的Pf 1和Xf株的衍射图可以解释为具有15 π螺距的蛋白质亚基的简单螺旋，在5圈中具有22个单位。每个蛋白质亚基在轴向方向上都是细长的，并且径向倾斜，以便彼此重叠，使亚基的排列让人联想到鱼的鳞片。蛋白质螺旋形成内径约20 μ m、外径约60 μ m的管。单股环状DNA包含在这个管中，有两条DNA链贯穿管的长度。fd，If 1和IKe（I类）的衍射图案可以解释为II类简单螺旋的扰动版本。
The diffraction patterns of the Pf 1 and Xf strains of filamentous bacterial viruses (class II) can be interpreted in terms of a simple helix of protein subunits with 15Åpitch, having 22 units in five turns. The protein subunits are each elongated in an axial direction, and also slope radially, so as to overlap each other, giving an arrangement of subunits reminiscent of scales on a fish. The protein helix forms a tube with inner diameter about 20Åand outer diameter about 60Å. The single-stranded circular DNA is contained within this tube, with two DNA strands running the length of the tube.The diffraction patterns of fd, If 1 and IKe (class I) can be interpreted in terms of a perturbed version of the class II simple helix.