A physiologic basis for red blood cell transfusion decisions
A physiologic basis for red blood cell transfusion decisions
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DOI：
10.1016/s0002-9610(99)80058-0
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发表时间：
1995-12-01
影响因子：
3
通讯作者：
Greenburg, AG
中科院分区：
文献类型：
--
作者：
Greenburg, AG
多年来，外科医生一直没有找到一种通用的“输血扳机”。在决定输注红细胞之前，应先优化心肺血流动力学。当全球供氧降至临界点以下，氧摄取和乳酸水平增加时，应考虑进行红细胞输注。目前，这些。必须使用侵入性技术监测参数。本文介绍了全球氧输送生理学的一些方面，这些方面似乎与心功能、新陈代谢和组织灌注有关。
Identification of a universal ''transfusion trigger'' has eluded surgeons for years. Optimization of cardiopulmonary hemodynamics should precede the decision to transfuse red blood cells. Red blood cell transfusion should be considered when global oxygen delivery falls below a critical point with increasing oxygen extraction and lactate levels. At present, these. parameters must be monitored with invasive techniques. This article addresses some aspects of global oxygen delivery physiology that appear to correlate with cardiac function, metabolism, and tissue perfusion.