Baroreflex function in sedentary and endurance-trained elderly people
Baroreflex function in sedentary and endurance-trained elderly people
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DOI：
10.1093/ageing/26.4.289
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发表时间：
1997-07-01
期刊：
影响因子：
6.7
通讯作者：
Ford, GA
中科院分区：
文献类型：
--
作者：
Bowman, AJ;Clayton, RH;Ford, GA
目的：探讨年龄和耐力运动训练对健康受试者压力反射功能的影响。设计：横断面研究。地点：大学研究部。研究对象：26名(10名女性)久坐健康、血压正常的老年受试者(平均年龄67岁，62-81岁)，8名(2名女性)老年耐力训练运动员(66岁，62-69岁)和8名(2名女性)年轻受试者(30岁，25-34岁)。测量：压力反射敏感性用阿尔法指数量化，在高频(HF，0.15-0.35赫兹)和中频(MF，0.15-0.35赫兹)结果：耐力训练运动员的静息心率显著低于久坐不动的老年人(58+/-12比68+/-11min(-1)，P<；0.05)，但与健康青年组(63+/-9min(-1))无差异。久坐不动的老年受试者α(HF)(8.1+/-4.2ms.mm Hg-1)低于耐力训练的老年运动员(14.8+/-4.8ms.mm Hg-1，P<；0.05)和健康青年受试者(28.3+/-21.8ms.mm Hg-1，P<；0.05)，而耐力训练的老年运动员与健康的年轻受试者之间差异无统计学意义(P=0.10)。健康青年组(15.4+/-8.8 ms.mm Hg-1)大于久坐不动组(6.5+/-3.2 ms.mm Hg-1，P<；0.01)和耐力训练老年运动员组(6.9+/-2.0 ms.mm Hg-1，P<；0.01)，但两组间差异无统计学意义(P=0.66)。结论：压力反射的两种成分均随年龄增长而降低。与久坐不动的老年受试者相比，接受耐力训练的老年运动员在OR指数的高频率成分(但不是中频率成分)方面下降得更少。压力感受器敏感性的某些年龄相关变化可能与身体健康和活动水平有关。
Objective: to determine the differences associated with age and endurance exercise training on the baroreflex function of healthy subjects.Design: cross-sectional study.Setting: university research department.Participants: 26 (10 female) sedentary healthy, normotensive elderly subjects (mean age 67 years, range 62-81), eight (two female) elderly endurance-trained athletes (66 years, 62-69) and eight (two female) young (30 years, 25-34) subjects.Measurements: baroreflex sensitivity was quantified by the alpha-index, at high frequency (HF, 0.15-0.35 Hz) and mid frequency (MF, 0.05-0.15 Hz), derived from spectral and cross-spectral analysis of spontaneous fluctuations in heart rate and blood pressure.Results: resting heart rate was significantly lower in endurance-trained athletes than sedentary elderly people (58 +/- 12 versus 68 +/- 11 min(-1), P < 0.05) but not different to that in healthy young subjects (63 +/- 9 min(-1)). alpha(HF) in sedentary elderly subjects (8.1 +/- 4.2 ms.mm Hg-1) was lower than both endurance-trained elderly athletes (14.8 +/- 4.8 ms.mm Hg-1, P < 0.05) and healthy young subjects (28.3 +/- 21.8 ms.mm Hg-1, P < 0.05) and was not significantly different between endurance-trained elderly athletes and healthy young subjects (P = 0.10). alpha(MF) in healthy young subjects (15.4 +/- 8.8 ms.mm Hg-1) was greater than in sedentary elderly subjects (6.5 +/- 3.2 ms.mm Hg-1, P < 0.01) and endurance-trained elderly athletes (6.9 +/- 2.0 ms.mm Hg-1, P < 0.01), while there was no significant difference between the two elderly groups (P = 0.66).Conclusions: both components of the baroreflex measured by the alpha-index show a decrease with age. Elderly endurance-trained athletes have less reduction in the high, but not mid, frequency component of the or-index compared with sedentary elderly subjects. Some of the age-related changes in baroreflex sensitivity may be related to physical fitness and activity levels.