The faster the better: anastomosis time influences patient survival after deceased donor kidney transplantation

The faster the better: anastomosis time influences patient survival after deceased donor kidney transplantation
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DOI:
10.1111/tri.12516
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发表时间:
2015-05-01
影响因子:
3.1
通讯作者:
Oellinger, Robert
Oellinger, Robert
中科院分区:
医学3区
文献类型:
--
作者:
Weissenbacher, Annemarie;Oberhuber, Rupert;Oellinger, Robert

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尽管对影响移植肾功能的因素(如供体年龄、体重指数和冷缺血时间)的了解不断增加,但关于吻合时间(AT)及其对长期结果的影响的数据很少。我们对因斯布鲁克医科大学2000年1月至2010年12月间1245例连续死亡供体肾移植患者进行回顾性分析,调查手术AT是否与肾移植后患者和移植物存活率相关。Kaplan-Meier和log-rank分析用于1年和5年患者和移植物存活。AT定义为从吻合开始到再灌注的时间。中位AT为30 min。AT > 30 min的移植物5年存活率为76.6%,AT组为80.6
Despite a continuously growing knowledge of the impact of factors on kidney graft function, such as donor age, body mass index, and cold ischemia time, few data are available regarding anastomosis time (AT) and its impact on long-term results. We investigated whether surgical AT correlates with patient and graft survival after kidney transplantation performing a retrospective analysis of 1245 consecutive deceased donor kidney transplantations between 01/2000 and 12/2010 at Innsbruck Medical University. Kaplan-Meier and log-rank analyses were carried out for 1- and 5-year patient and graft survival. AT was defined as time from anastomosis start until reperfusion. Median AT was 30min. Five-year survival of allografts with an AT >30min was 76.6% compared with 80.6% in the group with AT