Hospital-acquired infections-appropriate statistical treatment is urgently needed!
Hospital-acquired infections-appropriate statistical treatment is urgently needed!
复制标题
DOI：
10.1093/ije/dyt111
复制
发表时间：
2013-10-01
影响因子：
7.7
通讯作者：
Wolkewitz, Martin
中科院分区：
文献类型：
--
作者：
Schumacher, Martin;Allignol, Arthur;Wolkewitz, Martin
医院获得性感染（HAI）的研究需要最高的方法学标准，以最大限度地减少偏倚风险，避免误导性解释。有两个主要问题与这一领域的研究特别相关，即感染的时间和所谓竞争性风险的发生，值得特别注意。正如在住院期间获得严重感染的患者需要适当的抗生素治疗一样，在医院获得性感染研究中收集的数据需要适当的统计分析。我们说明了医院获得性感染的统计处理的迫切需要与最近进行的研究的一些例子，提出的考虑是相关的HAI的危险因素的调查，以及结果的研究。
Research on hospital-acquired infections (HAIs) requires the highest methodological standards to minimize the risk of bias and to avoid misleading interpretation. There are two major issues related specifically to studies in this area, namely the timing of infection and the occurrence of so-called competing risks, which deserve special attention. Just as a patient who acquires a serious infection during hospital admission needs appropriate antibiotic treatment, data being collected in studies on hospital-acquired infections need appropriate statistical analysis. We illustrate the urgent need for appropriate statistical treatment of hospital-acquired infections with some examples from recently conducted studies.The considerations presented are relevant for investigations on risk factors for HAIs as well as for outcome studies.