Sex differences in sensitization to cocaine-induced rotation.
Sex differences in sensitization to cocaine-induced rotation.
复制标题
对可卡因引起的轮换敏感性的性别差异。
DOI：
10.1016/0014-2999(84)90442-4
复制
发表时间：
1984
影响因子：
5
通讯作者：
Hinds,PA
中科院分区：
文献类型：
--
作者：
Glick,SD;Hinds,PA
在雄性和雌性大鼠中研究了可卡因和d-苯丙胺诱导旋转的致敏性。单次注射可卡因（20 mg/kg）使雌性大鼠对1天或7天后给予的后续剂量敏感;敏感性在14天内恢复正常。在雄性大鼠中未发生对可卡因的致敏作用，在两种性别中也未发生对d-苯丙胺的致敏作用。
Sensitization to cocaine- and d-amphetamine-induced rotation was studied in male and female rats. A single injection of cocaine (20 mg/kg) sensitized female rats to a subsequent dose administered 1 or 7 days later; sensitivity returned to normal within 14 days. Sensitization to cocaine did not occur in male rats nor to d-amphetamine in either sex.