Assessment of the interstitial fluid in the subcutaneous tissue of healthy adults using ultrasonography.
Assessment of the interstitial fluid in the subcutaneous tissue of healthy adults using ultrasonography.
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DOI：
10.1177/2050312115613351
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发表时间：
2015
影响因子：
2.3
通讯作者：
Sugama J
中科院分区：
文献类型：
--
作者：
Ueda-Iuchi T;Ohno N;Miyati T;Dai M;Okuwa M;Nakatani T;Sanada H;Sugama J
水肿包括肿胀，尤其是皮下组织。为了淋巴水肿的成功治疗，有必要清除间质液。皮下回声可能与间质液有关，但回声不是评价治疗的指标，因为我们没有直接比较回声与间质液。我们的目的是确定一个结果指标的评价间质液超声检查。我们评估了磁共振成像上回声与横向弛豫率（R2）之间的相关性。这是一项观察性研究。招募活动>8小时后腿部肿胀的健康成人。13名女性的腿部使用超声检查，磁共振成像和测量肢体周长之前和之后的干预，以减少肿胀进行评估。水肿组的回声强度大于对照组。回声强度随水肿减轻而降低。与R2变化的最强相关性范围发生在回声强度值为48-144时（Pearson相关系数：r =-0.63，p < 0.01）。因此，可以使用回声评价间质液。使用超声检查评价间质液的结局指标为回声强度在48-144范围内，这些值对于评估皮下组织中的间质液是有效的。
Lymphoedema involves swelling, especially in the subcutaneous tissues. For lymphoedema management to be successful, it is necessary to remove the interstitial fluid. Subcutaneous echogenicity may be associated with interstitial fluid, but echogenicity is not an indicator for the evaluation of management because we do not directly compare echogenicity with the interstitial fluid. We aimed to identify an outcome indicator for the evaluation of interstitial fluid using ultrasonography. We assessed the correlation between echogenicity and transverse relaxation rate (R2) on magnetic resonance imaging. This was an observational study. Healthy adults with leg swelling after activity for >8 h were recruited. The legs of 13 women were evaluated using ultrasonography, magnetic resonance imaging and measurements of the limb circumference before and after an intervention to reduce the swelling. Echogenicity in the oedema group was greater than that of the controls. Echogenicity decreased with reductions in oedema. The range of the strongest correlations with the changes in R2 occurred at echogenicity values of 48–144 (Pearson’s correlation coefficient: r = −0.63 and p < 0.01). Thus, it was possible to evaluate the interstitial fluid using echogenicity. The outcome indicators for the evaluation of interstitial fluid using ultrasonography were echogenicities in the range of 48–144, and these values were valid for assessing the interstitial fluid in the subcutaneous tissue.