Prevalence of and risk factors for hypoglycemic symptoms after gastric bypass and sleeve gastrectomy.
Prevalence of and risk factors for hypoglycemic symptoms after gastric bypass and sleeve gastrectomy.
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DOI：
10.1002/oby.21042
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发表时间：
2015-05
期刊：
影响因子：
6.9
通讯作者：
Brown, Todd T.
中科院分区：
文献类型：
--
作者：
Lee, Clare J.;Clark, Jeanne M.;Schweitzer, Michael;Magnuson, Thomas;Steele, Kimberley;Koerner, Olivia;Brown, Todd T.
确定减肥手术患者餐后低血糖症状的患病率和危险因素。将包括爱丁堡低血糖量表的问卷邮寄给在一个中心接受Roux-en-Y胃旁路术（RYGB）或垂直袖状胃切除术（VSG）的患者。根据调查问卷，我们将患者分为高度怀疑或低度怀疑手术后、餐后低血糖症状。在1119名具有有效地址的患者中，40.2%（N=450）做出了应答。在受访者中，34.2%高度怀疑减肥手术后低血糖症状。在多变量分析中，除了女性（p=0.001）、RYGB（p=0.004）、手术后时间较长（p=0.013）、无糖尿病（p=0.040）外，与低怀疑组相比，高怀疑组更可能报告术前低血糖症状（p<0.001）。当高度怀疑组仅限于需要他人帮助、晕厥、癫痫发作伴重度症状或经医学证实的低血糖时，观察到类似结果（N=52）。三分之一的RYGB或VSG报告了与术后低血糖相关的餐后症状，这与术前低血糖症状的存在有关。术前筛查低血糖症状可能会发现一组患者的减肥手术后低血糖风险增加。
To determine the prevalence of and risk factors for postprandial hypoglycemic symptoms among bariatric surgery patients. A questionnaire including the Edinburgh hypoglycemia scale was mailed to patients who underwent either Roux-en-Y gastric bypass (RYGB) or vertical sleeve gastrectomy (VSG) at a single center. Based on the questionnaire, we categorized the patients as having high or low suspicion for post-surgical, postprandial hypoglycemic symptoms. Of the 1119 patients with valid addresses, 40.2% (N=450) responded. Among the respondents, 34.2% had a high suspicion for symptoms of post-bariatric surgery hypoglycemia. In multivariate analyses, in addition to female sex (p=0.001), RYGB (p=0.004), longer time since surgery (p=0.013), lack of diabetes (p=0.040), the high suspicion group was more likely to report preoperative symptoms of hypoglycemia (p<0.001), compared to the low suspicion group. Similar results were observed when the high suspicion group was restricted to those requiring assistance from others, syncope, seizure with severe symptoms or medically confirmed hypoglycemia (N=52). One third of RYGB or VSG reported postprandial symptoms concerning for post-surgical hypoglycemia, which was related to the presence of pre-operative hypoglycemic symptoms. Pre-operative screening for hypoglycemic symptoms may identify a group of patients at increased risk of post-bariatric surgery hypoglycemia.
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影响因子：
8.2
作者：
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通讯作者：
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影响因子：
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DOI：
10.1016/j.jamcollsurg.2011.04.030
发表时间：
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影响因子：
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通讯作者：
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