Solvent-free copper/iron co-catalyzed N-arylation reactions of nitrogen-containing heterocycles with trimethoxysilanes in air
Solvent-free copper/iron co-catalyzed N-arylation reactions of nitrogen-containing heterocycles with trimethoxysilanes in air
复制标题
无溶剂铜/铁共催化空气中含氮杂环与三甲氧基硅烷的N-芳基化反应
DOI：
10.1016/j.tetlet.2007.08.117
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发表时间：
2007-10-29
影响因子：
1.8
通讯作者：
Li, Jin-Heng
中科院分区：
文献类型：
--
作者：
Song, Ren-Jie;Deng, Chen-Liang;Li, Jin-Heng
A solvent-free copper/iron-catalyzed N-arylation of nitrogen-containing heterocycles with trimethoxysilanes method for the formation of C-N bonds has been developed. In the presence of Cu, FeCl3, TBAF, and air, a variety of nitrogen-containing heterocycles including imidazoles and triazoles were coupled with aryltrimethoxysilanes and vinyltrimethoxysilane to afford the corresponding products in moderate to excellent yields. It is noteworthy that the reaction is conducted under solvent-free and relatively low Cu/FeCl3 loadings conditions. (C) 2007 Elsevier Ltd. All rights reserved.
