Failure of interferon alpha-2b in a patient with West Nile virus meningoencephalitis and acute flaccid paralysis
Failure of interferon alpha-2b in a patient with West Nile virus meningoencephalitis and acute flaccid paralysis
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DOI：
10.1080/00365540500262690
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发表时间：
2005-11-01
影响因子：
--
通讯作者：
Forrest, G
中科院分区：
文献类型：
--
作者：
Chan-Tack, KM;Forrest, G
WNV infection can cause meningoencephalitis (MNE) and acute flaccid paralysis (AFP). Both syndromes are associated with high morbidity and mortality. Interferon alpha-2b (IFN-alpha-2b) inhibits WNV replication in vitro. To date, 5 patients with WNV-CNS disease have recovered neurologic function with IFN-alpha-2b. We report the first failure of IFN-alpha-2b in the treatment of WNV-MNE-AFP.
