Photothermal and mechanical stimulation of cells via dualfunctional nanohybrids
Photothermal and mechanical stimulation of cells via dualfunctional nanohybrids
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DOI：
10.1088/0957-4484/27/47/475102
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发表时间：
2016-11-25
期刊：
影响因子：
3.5
通讯作者：
Miyako, Eijiro
中科院分区：
文献类型：
--
作者：
Chechetka, Svetlana A.;Doi, Motomichi;Miyako, Eijiro
Stimulating cells by light is an attractive technology to investigate cellular function and deliver innovative cell-based therapy. However, current techniques generally use poorly biopermeable light, which prevents broad applicability. Here, we show that a new type of composite nanomaterial, synthesized from multi-walled carbon nanotubes, magnetic iron nanoparticles, and polyglycerol, enables photothermal and mechanical control of Ca2+ influx into cells overexpressing transient receptor potential vanilloid type-2. The nanohybrid is simply operated by application of highly biotransparent near-infrared light and a magnetic field. The technology may revolutionize remote control of cellular function.
