A novel translucent ultrasound transducer approach for dual-modality ultrasound and photoacosutic imaging
A novel translucent ultrasound transducer approach for dual-modality ultrasound and photoacosutic imaging
复制标题
一种用于双模态超声和光声成像的新型半透明超声换能器方法
作者：
Mohamed Osman;Kevin P. Creamer;Haoyang Chen;Josiah Minotto;Jinyun Liu;S. Agrawal;Sri
透明超声换能器（TUT）最近成为开发多尺度光声成像（PAI）系统的一个有吸引力的平台。TUT允许在组织表面上轻松地将光学照明和声学检测路径共对准，避免了当前使用不透明传统超声换能器的PAI系统所采用的复杂光束排列。然而，由于缺乏合适的透明声学匹配和衬底层，tut的带宽较窄，灵敏度较低。为了解决上述挑战，在本研究中，我们探索了一种由悬浮在透明环氧树脂中的玻璃珠制成的新型光学半透明声学匹配层，以提高换能器的带宽/灵敏度和组织表面的光影响。我们对中心频率为13 MHz的涂覆不同玻璃珠浓度的tut进行的实验表明，脉冲回波带宽和灵敏度随玻璃珠浓度的增加而增加。使用声学匹配层为40%GB的TUT，测量到带宽提高了约3.3倍，脉冲回波灵敏度提高了2.5倍。进行了光学测量，以确认半透明玻璃珠层可以作为光漫射器，以帮助实现均匀的光分布在组织表面。
The transparent ultrasound transducer (TUT) has recently emerged as an attractive platform for development of multiscale photoacoustic imaging (PAI) systems. TUT allows an easy co-alignment of optical illumination and acoustic detection paths on the tissue surface, averting the complex beam arrangements employed by the current PAI systems that use opaque conventional ultrasound transducers. However, TUTs suffer from narrow bandwidth and low sensitivity due to the lack of suitable transparent acoustic matching and backing layers. To address the above challenges, in this study we explored a novel optically translucent acoustic matching layer made out of glass beads suspended in transparent epoxy to improve both the transducer bandwidth/sensitivity and light fluence on the tissue surface. Our experiments with 13 MHz center frequency TUTs coated with varying glass bead concentration demonstrated that both pulse-echo bandwidth and sensitivity increases with glass bead concentration. Approximately 3.3 fold improvement in bandwidth and a 2.5 times higher pulse-echo sensitivity was measured with TUT fabricated with an acoustic matching layer of 40%GB. Optical measurements were conducted to confirm that the translucent glass bead layer can act as a light diffuser to help achieve uniform light distribution on the tissue surface.
影响因子：
4
作者：
Fei, Chunlong;Ma, Jianguo;Zhou, Qifa
通讯作者：
Zhou, Qifa