TITANIUM IMPLANTS PERMANENTLY PENETRATING HUMAN-SKIN
TITANIUM IMPLANTS PERMANENTLY PENETRATING HUMAN-SKIN
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DOI：
10.3109/02844318209006565
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发表时间：
1982-01-01
影响因子：
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通讯作者：
ALBREKTSSON, T
中科院分区：
文献类型：
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作者：
BRANEMARK, PI;ALBREKTSSON, T
钛植入物被允许穿透8名人类志愿者的上臂皮肤，试图研究永久性植入物经皮通道的条件。如果使用限制植入物周围皮肤运动的结构，在7-25个月的随访期间，没有发现炎症或其他不利的软组织影响。在另一项对4名听力障碍患者的临床研究中，Ti植入物被牢固地固定在颞骨上，允许穿透皮肤，并直接连接外部助听器。在38-50个月的随访期间，这些经皮植入物的功能仍然没有任何问题。取得良好结果的原因可能与材料（非合金Ti）、植入物的设计和微创手术有关。新的治疗方法可能是使用外部假体通过穿透皮肤的机械连接固定在骨骼上，例如，在严重面部损伤的情况下，作为稳定和永久的附着体。目前正在进行这方面的临床试验。
Ti implants were allowed to penetrate the skin of the upper arm of 8 human volunteers in an attempt to investigate the conditions for a permanent implant transcutaneous passage. If a construction was used that restricted the skin movements around the implant no inflammatory or other adverse soft tissue effects were noted for follow-up periods of 7-25 mo. In another clinical investigation of 4 patients with hearing impairment, Ti implants were firmly anchored in the temporal bone, allowed to penetrate the skin and external hearing aids were directly attached. These transcutaneous implants are still functioning without any problems at a follow-up period of 38-50 mo. The reason for the favorable results achieved may be connected to the material (non-alloyed Ti), the design of the implant and a minimally traumatizing surgery. New treatments may be possible using external prostheses anchored to the skeleton via skin-penetrating mechanical connections as, e.g., stable and permanent episthesis attachment in cases of severe facial injuries. A clinical trial along these lines is presently being performed.