Design of an ultrasonic physiotherapy system with pulse wave feedback control.
Design of an ultrasonic physiotherapy system with pulse wave feedback control.
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DOI：
10.3233/thc-171334
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发表时间：
2017-07
期刊：
影响因子：
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通讯作者：
Ran Peng;Yang Luo;Zhangyong Li;Wei Wang;Yu Pang
中科院分区：
文献类型：
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作者：
Ran Peng;Yang Luo;Zhangyong Li;Wei Wang;Yu Pang
由于超声热疗和超声促渗背后的不同物理和生物机制，对超声功率、频率和控制模式的要求不同。目的：介绍一种基于实时监测患者生理特征的自适应超声理疗系统，为辅助康复提供个体化治疗和剂量限制。方法该方法利用人体心动周期的两个不同阶段（收缩期和舒张期）的独特特性作为调制媒介。心脏收缩期血流的丰富使得能够进行用于高热的能量交换，而由阿托洛尔引起的血流不足有助于药物渗透。所述方法可以改善辅助治疗，因为它提供了部分药物渗透和治疗剂量控制。结果通过调整多频超声的时间窗和强度，可以使照射剂量降低到1MHz连续照射剂量的22%左右。该方法在临床实践中显示出很高的潜力。结论调频超声治疗能更有效地促进药物渗透，提高热疗的疗效。
BACKGROUND Due to different physical and biological mechanisms behind ultrasound hyperthermia and phonophoresis, the requirement for ultrasound power, frequency and control modes varies. OBJECTIVE This paper introduces an adaptive ultrasonic physiotherapy system based on real-time surveillance over physiological characteristics of the patients, which in turn assists the individual treatment and dose limitation in auxiliary rehabilitation. METHODS The method essentially takes advantage of distinctive characteristics of two different phases (systole and diastole) of the human cardiac cycle as a medium for modulation. The abundance of blood flow during systole enables energy exchange for hyperthermia while blood flow insufficiency caused by diastole assists in drug penetration. Said method could improve the adjuvant therapy as it provides partial drug penetration and therapeutic dosage control. RESULTS By adjusting time window and intensity of multi-frequency ultrasound, it is possible to reduce the irradiation dosage to around 22% of that during continuous irradiation at 1 MHz. The method shows high potential in clinical practice. CONCLUSION Frequency-tuning ultrasound therapy would be more efficient regarding drug penetration and improve the therapeutic efficacy of hyperthermia.