When is a South Indian Really Anemic?
When is a South Indian Really Anemic?
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DOI：
10.1007/s12291-013-0386-0
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发表时间：
2014-10-01
影响因子：
2.1
通讯作者：
Reddy, P. S.
中科院分区：
文献类型：
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作者：
Pasupula, Deepak Kumar;Reddy, P. S.
为了确定印度南部健康成年人血红蛋白的正常范围和临界值，对177名男性和203名女性医学生的RBC和铁代谢参数进行了血液样本分析。这些数据与美国白色人群（NHANES III）和WHO贫血检测标准进行了比较。男学生的血红蛋白和红细胞压积的平均值与美国白色男性的差异很小。然而，除了总铁结合力（TIBC）较高外，铁代谢参数的值均较低。女生的血红蛋白、红细胞压积、铁代谢指标均低于美国白色女性，但总铁结合力高于美国白人女性。男性和女性的第5百分位数下限临界点（平均值-1.645 SD）分别为13.5和10 g/dl。总之，南印度成年男性的Hb值与美国成年男性相似，但南印度女性的Hb水平明显低于美国女性，这就提出了世卫组织或美国标准在印度女性贫血检测中的适用性问题。
To determine the normal range of Hemoglobin and cutoff values in healthy adults of Southern India, blood samples were analyzed for parameters of RBC and iron metabolism in 177 male and 203 female medical students. The data were compared with the American white population (NHANES III) and the WHO criteria for detection of anemia. The mean values for hemoglobin and hematocrit in male students differed minimally from American white males. However, values for parameters of iron metabolism were lower except total iron binding capacity (TIBC) which was higher. In female students, hemoglobin, hematocrit and parameters of iron metabolism were lower than American white females, except TIBC which was higher. Lower 5th percentile cutoff point (Mean - 1.645 SD) in males and females were 13.5 and 10 g/dl respectively. In conclusion, South Indian adult males have Hb values similar to American male adults, but South Indian females have considerably lower Hb levels than American females, raising the questions about appropriateness of WHO or US criteria for detection of anemia in Indian females.