Impact of prognostic factors on recovery from sudden hearing loss
Impact of prognostic factors on recovery from sudden hearing loss
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DOI：
10.1017/s0022215107005683
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发表时间：
2007-11-01
影响因子：
1.7
通讯作者：
Oezbilen, S.
中科院分区：
文献类型：
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作者：
Ceylan, A.;Celenk, F.;Oezbilen, S.
目的：明确患者相关参数和听前庭参数对突发性聋预后的影响。方法：83例患者纳入本回顾性研究。所有人都接受了药物治疗。我们记录了患者的人口统计学参数、全身疾病、突发性听力损失发作和开始治疗之间的时间、耳鸣、前庭症状、初始听力图类型、纯音平均值和言语辨别评分。结果：听力恢复率和听力增益评分与患者的性别、年龄无相关性（p> 0.05），听力恢复率和听力增益评分与患者的性别、年龄无相关性（p > 0.05）。然而，性别和相对听力增益之间存在相关性。眩晕与听力提高和恢复率评分无相关性（p < 0.05）。然而，相对听力增益与眩晕的存在呈负相关（-r = 0.05，81个自由度，p = 0.043）。入院时听力损失< 40 dB的患者表现出更好的相对听力增益（r = 0.55，81个自由度，p = 0.03）。相对听力增益与较好的治疗前言语辨别评分呈正相关（r = 0.82，81自由度，p = 0.009），与较差的治疗前纯音平均值呈负相关（-r = 0.082，81自由度，p = 0.009）。听力提高评分、相对听力提高评分及恢复率与全身疾病无相关性（p > 0.05）;突发性听力损失发作与开始治疗之间的时间（p > 0.05）;初次入院时听力图类型结论：突发性耳聋的预后不受全身疾病、耳鸣、听力图类型（中频型除外）的影响。以下是突发性听力损失预后不良的因素：女性，眩晕的存在，听力损失发作后超过7天开始治疗，入院时听力损失> 40 dB。
Objective: To define the impact of patient-related and audiovestibular parameters on the prognosis of sudden hearing loss.Methods: Eighty-three patients were included in this retrospective study. All were treated medically. We recorded the patients' demographic parameters, systemic diseases, time elapsed between onset of sudden hearing loss and initiation of treatment, tinnitus, vestibular symptoms, type of initial audiogram, pure tone averages and speech discrimination scores. For all patients, audiological measurements were performed on initial admission and at the completion of treatment on the 10th day.Results: There was no correlation between the hearing gain and recovery rate scores and patients' gender or age (p > 0.05). However, a correlation was found between gender and relative hearing gain. Vertigo was not correlated with hearing gain and recovery rate scores (p < 0.05). However, relative hearing gain correlated negatively with the presence of vertigo (-r = 0.05, 81 degrees of freedom, p = 0.043). Patients with < 40 dB hearing loss on admission showed a better relative hearing gain (r = 0.55, 81 degrees of freedom, p = 0.03). Relative hearing gain correlated positively with better pre-treatment speech discrimination scores (r = 0.82, 81 degrees of freedom, p = 0.009) and negatively with poorer pre-treatment pure tone averages (-r = 0.082, 81 degrees of freedom, p = 0.009). There was no correlation between the scores for hearing gain, relative hearing gain and recovery rate and: systemic diseases (p > 0.05); time elapsed between onset of sudden hearing loss and initiation of treatment (p > 0.05); type of audiogram on initial admission (p > 0.05), except for midfrequency type of audiogram; and tinnitus (p > 0.05).Conclusions: The outcome of sudden hearing loss was unaffected by systemic disease, tinnitus or type of audiogram (except for midfrequency type). The following were poor prognostic factors in the outcome of sudden hearing loss: female gender, presence of vertigo, initiation of treatment more than seven days after onset of hearing loss, and > 40 dB hearing loss on admission.