The KAT’s Out of the Bag: Histone Acetylation Promotes Centromere Assembly
The KAT’s Out of the Bag: Histone Acetylation Promotes Centromere Assembly
复制标题
KAT 揭秘:组蛋白乙酰化促进着丝粒组装
DOI:
10.1016/j.devcel.2016.05.019
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发表时间:
2016
影响因子:
11.8
通讯作者:
Mellone, Barbara G.
中科院分区:
文献类型:
--
作者:
Palladino, Jason;Mellone, Barbara G.
Heterochromatin is incompatible with centromeric chromatin assembly and propagation. In this issue ofDevelopmental Cell, Ohzeki et al. (2016) reveal that a critical role of the Mis18 complex is to transiently recruit the lysine acetyltransferase KAT7 to centromeres to facilitate the removal of H3K9me3 and the deposition of CENP-A.