Fat distribution in European women: a comparison of anthropometric measurements in relation to cardiovascular risk factors.

Fat distribution in European women: a comparison of anthropometric measurements in relation to cardiovascular risk factors.
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欧洲女性的脂肪分布:人体测量与心血管危险因素的比较。

DOI:
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发表时间:
1990
影响因子:
7.7
通讯作者:
G. D. Biase
G. D. Biase
中科院分区:
医学1区
文献类型:
--
作者:
J. Seidell;M. Cigolini;Jadviga Charzewska;B. Ellsinger;G. D. Biase

文献摘要

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在这项研究中,437名1948年出生的女性从5个欧洲城镇中选出,我们表明,一些人体测量值与38岁绝经前妇女的代谢风险状况一致且显著相关。围围中,调整体重指数后,胸围和腰围与舒张压、血清总胆固醇、高密度脂蛋白胆固醇(负相关)、血清甘油三酯和血清胰岛素呈正相关。测量腰围的最佳水平被确定为下肋骨缘和上髂前嵴之间的中间位置。围高比与舒张压、血清胆固醇和血清胰岛素的相关性不太一致、相似或较低。在研究的所有人体测量变量中,腰/大腿围比与高密度脂蛋白胆固醇和血清甘油三酯的部分相关性最强。作者得出结论,与肥胖程度无关,欧洲绝经前妇女的躯干脂肪分布指标(在乳房和腹部区域)与不利的风险状况有关。该研究为在流行病学研究中选择最具信息量的人体测量值添加到身高和体重中提供了理论依据。
In this study in 437 women born in 1948 selected from five European towns we show that several anthropometric measurements are consistently and significantly associated with a metabolic risk profile in premenopausal women of 38 years of age. Among the circumferences, breast and waist circumference were, after adjustment for body mass index positively correlated with diastolic blood pressure, serum total cholesterol, HDL-cholesterol (negative associations), serum triglycerides, and serum insulin. The optimal level for measuring waist circumference was determined as being midway between the lower rib margin and the superior anterior iliac crest. Circumference ratios generally did show less consistent and similar or lower correlations with diastolic blood pressure, serum cholesterol and serum insulin. Waist/thigh circumference ratio showed the strongest partial associations with HDL-cholesterol and serum triglycerides among all anthropometric variables studied. The authors conclude that, independently of the degree of fatness, indicators of truncal fat distribution (in the region of the breast as well as the abdomen) are related to an unfavourable risk profile in European premenopausal women. The study gives a rationale for selecting the most informative anthropometric measurements to be added to height and weight in epidemiological studies.