Impact of Ocular Surface Symptoms on Quality of Life in a United States Veterans Affairs Population
Impact of Ocular Surface Symptoms on Quality of Life in a United States Veterans Affairs Population
复制标题
DOI：
10.1016/j.ajo.2011.11.030
复制
发表时间：
2012-06-01
影响因子：
4.2
通讯作者：
Galor, Anat
中科院分区：
文献类型：
--
作者：
Pouyeh, Bozorgmehr;Viteri, Eduardo;Galor, Anat
目的：评价眼表症状对接受眼保健服务的退伍军人生活质量的影响。中心点设计：横断面调查研究。研究地点：迈阿密退伍军人事务医疗中心（VAMC）。患者人群：2010年6月至8月在眼科诊所就诊的患者被要求填写干眼问卷5 （DEQ5）和干眼对日常生活的影响问卷（IDEEL）。主要观察指标：眼表症状与眼功能的相关性。结果：489例患者选择填写DEQ5问卷（应答率36%）。受访者的平均年龄为66岁（标准差为12）。94%是男性；62%是白人，37%是黑人。使用DEQ5作为眼表症状的替代测量，65%的应答者报告了至少轻度眼表症状（DEQ5 >= 6）， 27%的应答者报告了严重症状（DEQ5 >= 12）。与白人受试者相比，黑人受试者出现严重症状的风险增加2倍（优势比2.06,95%可信区间1.333.19）。几种药物与严重症状的风险显著增加相关，包括青光眼药物（增加1.7倍）、抗抑郁药（增加2.3倍）和抗组胺药（增加2.1倍）。DEQ5和IDEEL评分在日常生活活动能力（n = 391, r = -0.54, P < .001）、情绪幸福感（n = 386, r = -0.63, P < .001）和工作能力（n = 205, r = -0.57, P < .001）方面呈负相关。50%有严重症状的患者有文件表明他们的症状在就诊期间得到了解决。结论：严重的眼表症状降低了迈阿密VAMC退伍军人的生活质量。眼保健专业人员应警惕引起患者的眼表抱怨。[J]中华眼科杂志，2012;33(3):1061-1066。(C) 2012年Elsevier Inc.版权所有。)
center dot PURPOSE: To evaluate the impact of ocular surface symptoms on quality of life in a veteran population receiving eye care services.center dot DESIGN: Cross-sectional survey study.center dot METHODS: SETTING: Miami Veterans Affairs Medical Center (VAMC). PATIENT POPULATION: Patients seen at the eye clinic between June and August 2010 were asked to fill out the Dry Eye Questionnaire 5 (DEQ5) and the Impact of Dry Eye on Everyday Life (IDEEL) questionnaire. MAIN OUTCOME MEASURES: Correlation between ocular surface symptoms and functionality.center dot RESULTS: Four hundred eighty-nine patients elected to fill out the DEQ5 questionnaire (36% response rate). The mean age of respondents was 66 years (standard deviation 12). Ninety-four percent were male; 62% were white and 37% were black. Using the DEQ5 as a surrogate measure of ocular surface symptoms, 65% of respondents reported at least mild ocular surface symptoms (DEQ5 >= 6) and 27% of them reported severe symptoms (DEQ5 >= 12). Black subjects had a 2-fold increased risk of severe symptoms compared to white subjects (odds ratio 2.06, 95% confidence interval 1.333.19). Several medications were associated with a significantly increased risk of severe symptoms, including glaucoma medications (1.7-fold increase), antidepressants (2.3-fold increase), and antihistamines (2.1-fold increase). There was an inverse correlation between DEQ5 and IDEEL scores with regard to ability to perform activities of daily living (n = 391, r = -0.54, P < .001), emotional well-being (n = 386, r = -0.63, P < .001), and the ability to work (n = 205, r = -0.57, P < .001). Fifty percent of patients with severe symptoms had documentation that their symptoms were addressed during the visit.center dot CONCLUSION: Severe ocular surface symptoms reduce the quality of life of Miami VAMC veterans. Eye care professionals should be vigilant in eliciting ocular surface complaints from their patients. (Am J Ophthalmol 2012;153:1061-1066. (C) 2012 by Elsevier Inc. All rights reserved.)