An analysis of polygenes affecting wing shape on chromosome 3 in Drosophila melanogaster.
An analysis of polygenes affecting wing shape on chromosome 3 in Drosophila melanogaster.
复制标题
影响果蝇 3 号染色体翅膀形状的多基因分析。
DOI：
10.1093/genetics/153.2.773
复制
发表时间：
1999
期刊：
影响因子：
3.3
通讯作者：
Zeng,ZB
中科院分区：
文献类型：
--
作者：
Weber,K;Eisman,R;Morey,L;Patty,A;Sparks,J;Tausek,M;Zeng,ZB
Loci on the third chromosome of Drosophila melanogaster that affect an index of wing shape were mapped, using recombinant isogenic lines, with transposable elements as markers. Many genes with small subequal effects are dispersed along the whole chromosome. Their alleles act nearly additively in heterozygotes. They have small correlated effects on leg shape, but no detectable effects on halteres. Small negative net interactions occur over most of the chromosome. The data set of 519 recombinant isogenic lines can be explained reasonably well by two models. One model posits an indefinitely large number of loci with no interactions. The other model posits 11 loci with additive effects whose sum equals the total phenotypic range and with large positive and negative interactions that nearly cancel each other.
