Margaret Kennard on sparing and recovery of function: a tribute on the 100th anniversary of her birth.
Margaret Kennard on sparing and recovery of function: a tribute on the 100th anniversary of her birth.
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DOI：
10.1076/jhin.8.3.269.1824
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发表时间：
1999-12-01
影响因子：
0.5
通讯作者：
Finger, S
中科院分区：
文献类型：
--
作者：
Finger, S
玛格丽特肯纳德是美国在功能保留和恢复实验研究方面的先驱。她最著名的实验是在20世纪30年代末和40年代初在耶鲁大学对猴子和猿进行的。通过描述脑损伤对婴儿、少年和老年灵长类动物的行为影响，她引起了人们对神经损伤时发育状态的重要性的新关注。肯纳德还进行了一些实验，这些实验表明，即使是成年灵长类动物也可以表现出明显的功能保留和恢复，特别是如果大脑损伤是分阶段而不是一次全部造成的。在许多方面，肯纳德通过证明除了损伤部位之外的几个因素也会影响损伤后的表现，并认识到如果神经重组确实发生，它可能发生在受损系统的幸存部分，从而帮助启动了关于功能保留和恢复的现代研究时代。
Margaret Kennard was an American pioneer in the experimental study of sparing and recovery of function. Her most famous experiments were performed on monkeys and apes at Yale University during the late 1930s and early 1940s. By describing the behavioral effects of brain damage on infantile, juvenile, and older primates, she drew new attention to just how important developmental status can be at the time of neural insult. Kennard also conducted experiments which showed that even adult primates can exhibit significant sparing and recovery of function, especially if brain lesions are made in stages rather than all at once. In many respects, Kennard helped launch the modern era of research on sparing and recovery of function by demonstrating that several factors in addition to lesion locus can affect post-injury performance and by recognizing that, if neural reorganization does occur, it probably takes place in spared parts of the damaged system.