Exercise blood pressure predicts mortality from myocardial infarction

Exercise blood pressure predicts mortality from myocardial infarction
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DOI:
10.1161/01.hyp.27.3.324
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发表时间:
1996-03-01
期刊:
影响因子:
8.3
通讯作者:
Erikssen, J
Erikssen, J
中科院分区:
医学1区
文献类型:
--
作者:
Mundal, R;Kjeldsen, SE;Erikssen, J

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从1972年到1975年,对1999名40 ~ 59岁的健康男性进行了研究,以确定在仰卧休息5分钟后随意测量血压是否能预测心肌梗死的发病率和死亡率。在31984患者-年(平均16年)的随访期间,235例受试者发生心肌梗死,其中143例为非致死性,92例为致死性。运动血压与心肌梗死发病率和死亡率的相关性比偶然血压更强。在520名偶然收缩压大于或等于140 mm Hg的男性中,304名男性在600 kpm/min的初始负荷下运动6分钟时收缩压升高至大于或等于200 mm Hg。这304名男性有心肌梗死的过度风险(18.8%对9.5%)。在1294名偶尔有血压的男性中,
Apparently healthy men (n=1999, 40 to 59 years old) were investigated from 1972 through 1975 to determine whether systolic blood pressure during bicycle ergometer exercise predicts morbidity and mortality from myocardial infarction beyond that of casual blood pressure taken after 5 minutes of supine rest. During a follow-up of 31 984 patient-years (average, 16 years), 235 subjects had myocardial infarctions, of which 143 were nonfatal and 92 were fatal. Exercise blood pressure was more strongly related than casual blood pressure to both morbidity and mortality from myocardial infarction. Among 520 men with casual systolic blood pressure greater than or equal to 140 mm Hg, 304 increased their systolic blood pressure to greater than or equal to 200 mm Hg during 6 minutes of exercise at an initial workload of 600 kpm/min. These 304 men had an excessive risk of myocardial infarction (18.8% versus 9.5% among the 1294 men with casual blood pressure