ESTIMATION OF THE EFFECTIVE SELF-DIFFUSION TENSOR FROM THE NMR SPIN-ECHO
ESTIMATION OF THE EFFECTIVE SELF-DIFFUSION TENSOR FROM THE NMR SPIN-ECHO
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DOI：
10.1006/jmrb.1994.1037
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发表时间：
1994-03-01
期刊：
影响因子：
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通讯作者：
LEBIHAN, D
中科院分区：
文献类型：
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作者：
BASSER, PJ;MATTIELLO, J;LEBIHAN, D
有效自扩散张量D（eff）的对角和非对角元素与NMR自旋回波实验中的回波强度有关。这个关系被用来设计实验，D（eff）估计。该估计使用各向同性和各向异性介质进行验证，即，水和骨骼肌。结果表明，显着的错误是在扩散NMR光谱和成像的各向异性骨骼肌时，非对角元素D（eff）被忽略，最显着的损失所需的信息，以确定纤维取向。D（eff）的估计为新的MRI模态（扩散张量成像）提供了理论基础，扩散张量成像提供关于组织微观结构及其生理状态的信息，所述信息不包含在标量中，诸如T1、T2、质子密度或标量表观扩散常数。(C)1994年出版社出版。
The diagonal and off-diagonal elements of the effective self-diffusion tensor, D(eff), are related to the echo intensity in an NMR spin-echo experiment. This relationship is used to design experiments from which D(eff) is estimated. This estimate is validated using isotropic and anisotropic media, i.e., water and skeletal muscle. It is shown that significant errors are made in diffusion NMR spectroscopy and imaging of anisotropic skeletal muscle when off-diagonal elements of D(eff) are ignored, most notably the loss of information needed to determine fiber orientation. Estimation of D(eff) provides the theoretical basis for a new MRI modality, diffusion tensor imaging, which provides information about tissue microstructure and its physiologic state not contained in scalar quantities such as T1, T2, proton density, or the scalar apparent diffusion constant. (C) 1994 Academic Press, Inc.