Motion of both mitral valve leaflets: a cineroentgenographic study in intact dogs.
Motion of both mitral valve leaflets: a cineroentgenographic study in intact dogs.
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两个二尖瓣小叶的运动：完整狗的电影摄影研究。
DOI：
10.1152/jappl.1975.39.3.359
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发表时间：
1975
影响因子：
3.3
通讯作者：
L. Irving
中科院分区：
文献类型：
--
作者：
A. Tsakiris;D. A. Gordon;Y. Mathieu;L. Irving
在5只正常犬的瓣尖和二尖瓣环上缝合不透射线标记物后1-11周，研究了二尖瓣双瓣叶的运动和位置。采用左心房和左心室的荧光电影和血管电影（100-120帧/秒）研究瓣尖运动和心室内血流模式，并检测窦性心律（42-184次/分）和孤立性心房或心室收缩期间的二尖瓣返流。除后尖开放延迟外，整个二尖瓣期间两个瓣叶的时间运动相似。从ECG的Q波测量的峰开放和闭合速度、开放和闭合时间以及完全闭合时间不受心率变化的显著影响。舒张期瓣叶闭合在打开后立即开始，而心室腔较小，并且是由瓣尖后面的流动漩涡引起的。单独心室收缩使瓣叶完全闭合，通过不同的瓣叶边缘对合率确保对称瓣膜闭合。相比之下，心房关闭缓慢，部分，持续时间非常短。
Motion and position of both mitral leaflets were studied in five normal dogs 1-11 wk after radiopaque markers were sutured on the valve cusps and on the mitral annulus. Cinefluorograms and cineangiograms (100-120 frames/s) of left atrium and left ventricle were used to study cusp motion and intraventricular flow patterns, and to detect mitral regurgitation during sinus rhythm (42-184 beats/min) and during isolated atrial or ventricular contractions. Time-motion of both leaflets was similar throughout diastole with the exception of delayed posterior cusp opening. Peak opening and closing speeds, opening and closing times, and time of complete closure, measured from the Q wave of the ECG, were not significantly affected by the variations in heart rate. Diastolic leaflet closure began immediately after opening, while the ventricular cavity was small, and was caused by flow eddies behind the cusps. Isolated ventricular contractions closed the valve leaflets completely and symmetric valve closure was ensured by the different rates of leaflet edge approximation. In contrast, atrial closure was slow, partial, and of very short duration.