Parental history of hypertension and cardiovascular responses to behavioral stress in young black women.
Parental history of hypertension and cardiovascular responses to behavioral stress in young black women.
复制标题
年轻黑人女性的父母高血压史和心血管对行为压力的反应。
DOI：
10.1016/0022-3999(87)90021-3
复制
发表时间：
1987
影响因子：
4.7
通讯作者：
Muranaka,M
中科院分区：
文献类型：
--
作者：
Anderson,NB;WilliamsJr,RB;Lane,JD;Houseworth,S;Muranaka,M
β-肾上腺素能交感神经系统（SNS）对行为应激的高反应性可能在持续性高血压的发病中起作用，特别是在父母有高血压病史的人中。虽然高血压在黑人中非常普遍，但在这一群体中，父母高血压史与心血管高反应性之间的关系尚未探讨。本研究探讨了一组年轻黑人女性的父母高血压史对心血管应激反应的影响。与以前的白人研究结果相反，父母有高血压史的黑人受试者表现出显着较小的收缩压和前臂血流量增加，并适度较小的舒张压增加的任务。在每个实验条件下，父母病史受试者也表现出较慢的心率。结果表明，黑人高血压风险可能不会表现出在白人中观察到的行为应激的β-肾上腺素能高反应性。这些结果可能表明，β-肾上腺素介导的高反应性可能较少参与黑人高血压的发展。
Beta-adrenergic sympathetic nervous system (SNS) hyperresponsivity to behavioral stress may play a role in the onset of sustained high blood pressure—particularly in persons with a parental history of hypertension. Although hypertension is extremely prevalent among blacks, the association between parental history of hypertension and cardiovascular hyperresponsivity has not been explored in this group. The present study examined the influence of parental history of hypertension on cardiovascular stress reactivity in a group of young black females. Contrary to previous findings with whites, black subjects with a parental history of hypertension exhibited significantly smaller systolic blood pressure and forearm blood flow increases, and moderately smaller diastolic blood pressure increases to the task. Parental history subjects also exhibited slower heart rates throughout each experimental condition. The results suggest that blacks at risk from hypertension may not exhibit the beta-adrenergic hyperresponsivity to behavioral stress observed in whites. These results may suggest that beta-adrenergically mediated hyperresponsivity may be less involved in the development of hypertension among blacks.