No evidence for HTLV-I infection in 24 cases of French and Portuguese mycosis fungoïdes and Sezary syndrome (as seen in France).
No evidence for HTLV-I infection in 24 cases of French and Portuguese mycosis fungoïdes and Sezary syndrome (as seen in France).
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在 24 例法国和葡萄牙蕈样肉芽肿和塞扎里综合征病例中，没有证据表明 HTLV-I 感染（如法国所见）。
作者：
C. Capesius;F. Saal;E. Maero;A. Bazarbachi;J. Lasneret;L. Laroche;A. Gessain;F. Hojman;J. Périès
为寻找HTLV-I感染的证据，对居住在法国的诊断为真菌病fungoïdes或Sezary综合征的法国和葡萄牙患者进行了调查。研究方法包括血清学分析（ELISA、Western blot、颗粒凝集、间接免疫荧光）和DNA分子研究（Southern blot和聚合酶链反应）。用电镜和逆转录酶法检测外周血单个核细胞的培养情况。结果表明，HTLV-I和一种密切相关的逆转录病毒在研究的病例中与真菌病fungoïde或Sezary综合征无关。
A survey in search of evidence for HTLV-I infection was conducted on French and Portuguese patients residing in France with a diagnosis of mycosis fungoïdes or Sezary syndrome. Methods used in this investigation included serological assays (ELISA, Western blot, particle agglutination, indirect immunofluorescence) and DNA molecular studies (Southern blot and polymerase chain reaction). Cultures of peripheral blood mononuclear cells were performed and checked by electron microscopy and reverse transcriptase assay. The results indicate that neither HTLV-I nor a closely related retrovirus are associated with mycosis fungoïde or Sezary syndrome in the cases studied.