Behavioral therapy intervention trial to improve sleep quality and cancer-related fatigue
Behavioral therapy intervention trial to improve sleep quality and cancer-related fatigue
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DOI：
10.1002/pon.1438
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发表时间：
2009-06-01
期刊：
影响因子：
3.6
通讯作者：
Von Essen, Susanna G.
中科院分区：
文献类型：
--
作者：
Berger, Ann M.;Kuhn, Brett R.;Von Essen, Susanna G.
背景资料：为了确定是否可以改善与乳腺癌辅助化疗治疗相关的睡眠质量和疲劳与行为疗法（BT）[个性化睡眠促进计划（ISPP（C））]，包括修改刺激控制，修改睡眠限制，放松疗法，和sleephygienics.Methods：基于Piper综合疲劳模型，219 I-IIIA期乳腺癌患者的随机对照试验。在最初的化疗治疗之前，BT参与者制定了一个ISPP计划，并定期加强和修订。对照组接受健康饮食信息和关注。在每次治疗前2天、每次治疗后7天和末次治疗后30天收集匹兹堡睡眠质量指数（PSQI）、每日日记、活动记录仪和Piper疲劳量表（PFS）数据。重复测量方差分析used.Results：化疗前，参与者报告轻度疲劳和相当差的睡眠质量。所有变量都随着时间的推移而变化。BT组的睡眠质量（PSQI）改善与时间的相互作用有关。日记显示组间觉醒次数、入睡后清醒分钟数和睡眠效率存在差异。两组之间的疲劳（PFS）相似。结论：BT组随着时间的推移睡眠质量有所改善，睡眠更好（日记）。随着时间的推移，睡眠质量改善的感知与日记或活动记录仪并不一致，也不会导致较低的疲劳。版权所有（C）2008约翰威利父子有限公司
Background: To determine whether sleep quality and fatigue associated with breast cancer adjuvant chemotherapy treatments can be improved with behavioral therapy (BT) [Individualized Sleep Promotion Plan (ISPP(C))] including modified stimulus control, modified sleep restriction, relaxation therapy, and sleep hygiene.Methods: Randomized-controlled trial based on Piper Integrated Fatigue Model, 219 stages I-IIIA breast cancer patients. Prior to the initial chemotherapy treatment, BT participants developed an ISPP plan that was regularly reinforced and revised. Controls received healthy eating information and attention. Pittsburgh Sleep Quality Index (PSQI), daily diary, actigraph, and Piper Fatigue Scale (PFS) data were collected 2 days prior, during the 7 days after each treatment, and 30 days after the last treatment. Repeated measures analysis of variance was used.Results: Prior to chemotherapy, participants reported mild fatigue and fairly poor sleep quality. All variables changed over time. A group by time interaction was found for sleep quality (PSQI) improving in the BT group. Diary revealed group differences on number of awakenings, minutes awake after sleep onset, and sleep efficiency. Fatigue (PFS) was similar between groups.Conclusions: The BT group showed improved sleep quality over time and better sleep (diary). Perceptions of improved sleep quality over time are not consistently associated with diary or actigraph, or result in lower fatigue. Copyright (C) 2008 John Wiley & Sons, Ltd.