LTCC based microfluidic system with optical detection
LTCC based microfluidic system with optical detection
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DOI：
10.1016/j.snb.2005.03.065
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发表时间：
2005-11-11
影响因子：
8.4
通讯作者：
Stadnik, D
中科院分区：
文献类型：
--
作者：
Golonka, LJ;Roguszczak, H;Stadnik, D
设计、制造和测试了一种简单、廉价的集成光纤和温度控制系统的低温共烧陶瓷（LTCC）微流控装置。作为第一步，制造具有混合曲折、Y形试剂接头和流体输入/输出的测试结构，以检查混合有效性、密封性，并进行压力测试。肌酸酐的标准溶液用于透射率测量。通过Cu（NH3）（4）（2+）和荧光素溶液分别对LTCC模块中集成有光纤的检测系统的透射率和荧光测量进行评估。所构建的结构被发现是一个非常有用的化学分析装置。(c)2005 Elsevier B. V.保留所有权利。
The simple and inexpensive Low Temperature Cofired Ceramics (LTCC) microfluidic device with an integrated fiber optics and a temperature control system is designed, manufactured and tested. As the first step, the test structure with mixing meander, a Y-shape reagents junction and fluid inputs/output is made in order to check mixing effectiveness, leak proofness, and to carry out pressure tests. Standard solutions of creatinine are used for transmittance measurements. The detection system with optical fibers integrated in the LTCC module is evaluated for transmittance and fluorescence measurements by solution of Cu(NH3)(4)(2+) and fluorescein, respectively. The constructed structure is found to be a very useful device in chemical analysis. (c) 2005 Elsevier B.V. All rights reserved.