Endobronchial Ultrasound Image Simulation for Image-Guided Bronchoscopy.
Endobronchial Ultrasound Image Simulation for Image-Guided Bronchoscopy.
复制标题
用于图像引导支气管镜检查的支气管内超声图像模拟。
DOI：
10.1109/tbme.2022.3190165
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发表时间：
2023
期刊：
影响因子：
--
通讯作者：
Higgins,WilliamE
中科院分区：
文献类型：
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作者：
Zhao,Wennan;Ahmad,Danish;Toth,Jennifer;Bascom,Rebecca;Higgins,WilliamE
背景/目的准确的疾病诊断和分期对于疑似肺癌患者至关重要。医生执行这些手术时使用的最先进的微创工具是用于导航肺气道的支气管镜检查和用于定位可疑的管腔外癌症病变的支气管内超声 (EBUS)。虽然新的图像引导系统能够在病变附近进行精确的支气管镜导航，但没有任何方法可以指导管腔外病变的最终 EBUS 定位。我们提出了一种 EBUS 模拟方法来协助 EBUS 定位。方法该方法利用患者的胸部计算机断层扫描 (CT) 扫描来模拟超声信号通过组织介质的传播。该方法适用于模拟径向探针和凸面探针 EBUS 设备的 EBUS 图像，需要三个步骤：1）图像预处理，生成 EBUS 扫描平面的 2D CT 等效项； 2）EBUS扫描线计算，对超声传输进行建模，将CT平面映射成初步模拟的EBUS图像； 3) 图像后处理，通过引入模拟 EBUS 成像效果和伪影来增加真实感。结果结果表明，该方法生成的模拟 EBUS 图像与真实设备实时生成的图像非常相似，并且与现有的超声模拟方法相比毫不逊色。它还以高于实时的速率（即 53 帧/秒）生成图像。我们还展示了该方法成功集成到图像引导 EBUS 支气管镜检查系统中。结论/意义该方法对于 EBUS 支气管镜检查的手术计划/预览和后续实时指导是有效且实用的。
Background/ObjectiveAccurate disease diagnosis and staging are essential for patients suspected of having lung cancer. The state-of-the-art minimally invasive tools used by physicians to perform these operations are bronchoscopy, for navigating the lung airways, and endobronchial ultrasound (EBUS), for localizing suspect extraluminal cancer lesions. While new image-guided systems enable accurate bronchoscope navigation close to a lesion, no means exists for guiding the final EBUS localization of an extraluminal lesion. We propose an EBUS simulation method to assist with EBUS localization.MethodsThe method draws on a patient's chest computed-tomography (CT) scan to model the ultrasound signal propagation through the tissue media. The method, which is suitable for simulating EBUS images for both radial-probe and convex-probe EBUS devices, entails three steps: 1) image preprocessing, which generates a 2D CT equivalent of the EBUS scan plane; 2) EBUS scan-line computation, which models ultrasound transmission to map the CT plane into a preliminary simulated EBUS image; and 3) image post-processing, which increases realism by introducing simulated EBUS imaging effects and artifacts.ResultsResults show that the method produces simulated EBUS images that strongly resemble images generated live by a real device and compares favorably to an existing ultrasound simulation method. It also produces images at a rate greater than real time (i.e.,53 frames/sec). We also demonstrate a successful integration of the method into an image-guided EBUS bronchoscopy system.Conclusion/SignificanceThe method is effective and practical for procedure planning/preview and follow-on live guidance of EBUS bronchoscopy.