Higher pre-pregnancy body mass index is associated with excessive gestational weight gain in normal weight Chinese mothers with gestational diabetes

Higher pre-pregnancy body mass index is associated with excessive gestational weight gain in normal weight Chinese mothers with gestational diabetes
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对于体重正常的中国妊娠期糖尿病母亲来说,较高的孕前体重指数与妊娠期体重过度增加有关。

DOI:
10.1111/jog.12934
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发表时间:
2016-05-01
影响因子:
1.6
通讯作者:
Wang, Shaohua
Wang, Shaohua
中科院分区:
医学4区
文献类型:
--
作者:
Yang, Yue;Wei, Qiong;Wang, Shaohua

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目的 评估妊娠期糖尿病 (GDM) 女性队列中孕前体重指数 (BMI) 如何影响妊娠结局和妊娠总体重 (GWG)。方法将诊断为 GDM 的孕 24-28 周孕妇分为正常体重(孕前 BMI,18.5-24.9 kg/m(2))或超重(孕前 BMI, 25.0-29.9 千克/米(2))。 GWG 源自自我报告的孕前和分娩前体重,并使用 2009 年医学研究所分类进行分析。结果 共有 106 名 GDM 女性被分类为正常体重 (n = 79) 或超重 (n = 27)。各组之间在各种产科和新生儿结局方面没有发现统计学上的显着差异。然而,较高的孕前 BMI 与怀孕期间过多的 GWG 相关(组间差异,P = 0.013)。此外,孕前BMI(OR,0.529;95%CI:0.377-0.742;P=0.000)和孕前超重(OR,3.825;95%CI:1.469-9.959;P=0.006)是GWG的独立影响因素。结论在中国GDM女性中,超重的GDM母亲体重增加过多。怀孕期间。孕前体重调节可能是防止体重增加过多的适当预防措施。
AimTo assess how pre-pregnancy body mass index (BMI) affects pregnancy outcome and total gestational weight gain (GWG) in a cohort of women with gestational diabetes (GDM).MethodsPregnant women at 24-28 gestational weeks diagnosed with GDM were classified as normal weight (pre-pregnancy BMI, 18.5-24.9 kg/m(2)) or overweight (pre-pregnancy BMI, 25.0-29.9 kg/m(2)). GWG was derived from the self-reported pre-pregnancy and pre-delivery weights, and analyzed using 2009 Institute of Medicine categories.ResultsA total of 106 GDM women were categorized as normal weight (n = 79) or overweight (n = 27). No statistically significant differences were found between the groups in terms of various obstetrical and neonatal outcomes. Higher pre-pregnancy BMI, however, was associated with excessive GWG during pregnancy (difference between groups, P = 0.013). Furthermore, pre-pregnancy BMI (OR, 0.529; 95%CI: 0.377-0.742; P = 0.000) and pre-pregnancy overweight (OR, 3.825; 95%CI: 1.469-9.959; P = 0.006) were independent factors of GWG.ConclusionsAmong Chinese GDM women, overweight GDM mothers gain excessive weight during pregnancy. Regulation of pre-pregnancy bodyweight might be an appropriate precaution against excessive GWG.