Morphological aberrations of nutritionally deficient streptococci: association with pyridoxal (vitamin B6) concentration and potential role in antibiotic resistance
Morphological aberrations of nutritionally deficient streptococci: association with pyridoxal (vitamin B6) concentration and potential role in antibiotic resistance
复制标题
营养缺乏型链球菌的形态畸变：与吡哆醛（维生素 B6）浓度的关联以及抗生素耐药性中的潜在作用
作者：
R. B. Clark;R. Gordon;E. Bottone;M. Reitano
一株营养不良的链球菌根据生长培养基中吡哆醇的浓度表现出形态畸变。在电子显微镜下观察到丝状杆状细胞，在浓度下降的情况下占主导地位。外细胞壁的多次内陷表明二元裂变受到抑制。在相似吡哆醛浓度下进行的青霉素抗菌研究表明丝状菌形式与青霉素敏感性之间存在关系。
A strain of a nutritionally deficient streptococcus was shown to undergo morphological aberrations according to pyridoxal concentrations in the growth medium. Filamentous rod-shaped cells, observed by electron microscopy, predominated in the presence of decreasing concentrations. Multiple invaginations in the outer cell wall suggested inhibition of binary fission. Penicillin antimicrobial studies performed in the presence of similar pyridoxal concentrations indicated a relationship between filamentous forms and penicillin susceptibility.