Copper complexes as a source of redox active MRI contrast agents
Copper complexes as a source of redox active MRI contrast agents
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DOI：
10.1007/s10534-015-9875-3
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发表时间：
2015-10-01
期刊：
影响因子：
3.5
通讯作者：
Spickett, Corinne M.
中科院分区：
文献类型：
--
作者：
Dunbar, Lynsey;Sowden, Rebecca J.;Spickett, Corinne M.
该研究报告了在设计铜基氧化还原传感MRI造影剂方面的进展。虽然数据表明，铜（II）配合物是不能够与镧系元素物种的对比度方面的竞争，氧化还原依赖的开关之间的抗磁性铜（I）和顺磁性铜（II）产生一种新的氧化还原敏感的对比部分具有可逆性的潜力。
The study reports an advance in designing copper-based redox sensing MRI contrast agents. Although the data demonstrate that copper(II) complexes are not able to compete with lanthanoids species in terms of contrast, the redox-dependent switch between diamagnetic copper(I) and paramagnetic copper(II) yields a novel redox-sensitive contrast moiety with potential for reversibility.