Mephedrone use and associated adverse effects in school and college/university students before the UK legislation change
Mephedrone use and associated adverse effects in school and college/university students before the UK legislation change
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DOI：
10.1093/qjmed/hcq134
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发表时间：
2010-11-01
影响因子：
13.3
通讯作者：
Wood, D. M.
中科院分区：
文献类型：
--
作者：
Dargan, P. I.;Albert, S.;Wood, D. M.
方法：于2010年2月在英国苏格兰泰赛德地区的中学、学院和大学进行问卷调查。结果：共有1006人完成调查，其中男生501人(49.8%)，女生505人(50.2%)，其中349人将所在教育机构归类为学校，657人归类为学院/大学。其中205人(20.3%)报告曾使用甲氧麻黄酮；23.4%的人报告以前只使用过一次，尽管4.4%的人报告每天使用。在使用过甲氧麻黄酮的患者中，共有56%的人报告了至少一种与使用甲氧麻黄酮有关的不良反应。共有17.6%的吸毒者报告了与使用甲氧麻黄酮有关的上瘾或依赖症状。48.8%的用户从街头经销商处购买甲氧麻黄酮，10.7%的用户从互联网上购买。结论：本研究表明，甲氧麻黄酮在中小学生和大学生中的使用很普遍，而且用户认为它很容易获得。与使用它相关的有害影响的发生率很高。还需要进一步的工作来确定最近英国立法中关于甲氧麻黄酮和其他相关卡西酮的变化的影响，以及这是否有效地降低了甲氧麻黄酮的使用率。
Methods: Data was collected using a questionnaire survey in schools, colleges and universities in the Tayside area of Scotland, UK in February 2010.Results: A total of 1006 individuals completed the survey [501 (49.8%) males and 505 (50.2%) females], of whom 349 classified their educational institute as a school and 657 as a college/university. Among them 205 (20.3%) reported previous use of mephedrone; 23.4% reported using only using mephedrone on one occasion previously, although 4.4% reported daily use. A total of 56% of those who had used mephedrone, reported at least one unwanted effect associated with its use. A total of 17.6% of users reported 'addiction or dependence' symptoms associated with their mephedrone use. A total of 48.8% of users sourced mephedrone from street level dealers, 10.7% from the Internet.Conclusions: We have shown in this study that the use of mephedrone among school and college/university students is common and that users found it easy to obtain. There was a high prevalence of unwanted effects associated with its use. Further work is needed to determine the impact of the recent changes in the UK legislation relating to mephedrone and other related cathinones and whether this has been effective in reducing the prevalence of mephedrone use.