The role of cutaneous afferents from the distal hindlimb in the regulation of the step cycle of thalamic cats
The role of cutaneous afferents from the distal hindlimb in the regulation of the step cycle of thalamic cats
复制标题
后肢远端皮肤传入在丘脑猫步态周期调节中的作用
DOI：
10.1007/bf00235013
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发表时间：
1976
影响因子：
2
通讯作者：
K. Pearson
中科院分区：
文献类型：
--
作者：
J. Duysens;K. Pearson
在丘脑猫中，电刺激足垫和足底表面。弱刺激诱发动物在休息时的伸肌反射。同样的刺激在一个自发行走的动物在站立阶段期间施加产生的幅度和持续时间的增加正在进行的伸肌活动。当在摆动阶段，刺激延长正在进行的屈肌活动和/或缩短以下伸肌爆发。这些屈肌和伸肌爆发持续时间的变化反映在步进周期持续时间的变化上。直接刺激腓肠神经也观察到类似的结果。对于后者的实验，同侧后肢固定和失神经支配，除了踝关节伸肌和屈肌，这表明节律性收缩与其余三个肢体的步行运动正常相关。在休息时，阈值刺激腓肠神经引起的反射性收缩小腿三头肌的固定腿。在步行过程中，在固定小腿三头肌的收缩阶段施加相同的刺激，导致更大和更长的伸肌收缩和以下屈曲的延迟。在固定小腿三头肌的放松阶段进行刺激会缩短随后收缩阶段的持续时间。研究结果进行了讨论，在运动过程中的皮肤输入的可能作用。
SummaryThe pad and the plantar surface of the foot were stimulated electrically in thalamic cats. Weak stimulation evoked an extensor reflex in the animal at rest. The same stimuli in a spontaneously walking animal applied during the stance phase produced an increase both in amplitude and duration of the ongoing extensor activity. When given during the swing phase, the stimuli either prolonged the ongoing flexor activity and/or shortened the following extensor burst. These changes in flexor and extensor burst duration were reflected in changes in the step cycle duration.Similar results were seen with direct stimulation of the sural nerve. For the latter experiments the ipsilateral hindlimb was fixed and denervated except for the ankle extensors and flexors, which showed rhythmic contractions correlated normally with the walking movements of the three remaining limbs. At rest, threshold stimulation of the sural nerve evoked a reflex contraction in the triceps surae of the fixed leg. The same stimuli applied during the contraction phase of the fixed triceps surae during walking resulted in a larger and longer extensor contraction and a delay of the following flexion. Stimulation during the relaxation phase of the fixed triceps surae reduced the duration of the following contraction phase. The findings are discussed in relation to the possible role of cutaneous input during locomotion.