The effects of psychotherapy for adult depression are overestimated: a meta-analysis of study quality and effect size

The effects of psychotherapy for adult depression are overestimated: a meta-analysis of study quality and effect size
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DOI:
10.1017/s0033291709006114
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发表时间:
2010-02-01
影响因子:
6.9
通讯作者:
Andersson, G.
Andersson, G.
中科院分区:
医学1区
文献类型:
--
作者:
Cuijpers, P.;van Straten, A.;Andersson, G.

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背景没有元分析研究已经检查了是否研究的质量检查心理治疗成人抑郁症的影响大小发现。我们使用了一个包含115项随机对照试验的数据库,其中178项针对成人抑郁症的心理治疗与对照条件进行了比较。8个质量标准由两个独立的编码器进行评估:参与者符合抑郁症的诊断标准,使用治疗手册,治疗师接受培训,检查治疗完整性,使用意向治疗分析,N >= 50,由独立方进行随机化,结果评估者设盲。只有11项研究(16项比较)符合8项质量标准。高质量研究的标准化平均效应量(d=0.22)显著小于其他研究(d=0.74,p
Background. No meta-analytical study has examined whether the quality of the Studies examining psychotherapy for adult depression is associated with the effect sizes found. This study assesses this association.Method. We used a database of 115 randomized controlled trials in which 178 psychotherapies for adult depression were compared to a control condition. Eight quality criteria were assessed by two independent coders: participants met diagnostic criteria for a depressive disorder, a treatment manual was used, the therapists were trained, treatment integrity was checked, intention-to-treat analyses were used, N >= 50, randomization was Conducted by an independent party, and assessors of outcome were blinded.Results. Only 11 studies (16 comparisons) met the eight quality criteria. The standardized mean effect size found for the high-quality studies (d=0.22) was significantly smaller than in the other Studies (d=0.74, p