Internet-based screening for Chlamydia trachomatis to reach nonclinic Populations with mailed self-administered vaginal swabs
Internet-based screening for Chlamydia trachomatis to reach nonclinic Populations with mailed self-administered vaginal swabs
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DOI：
10.1097/01.olq.0000200497.14326.fb
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发表时间：
2006-07-01
影响因子：
3.1
通讯作者：
Hogan, M. Terry
中科院分区：
文献类型：
--
作者：
Gaydos, Charlotte A.;Dwyer, Karen;Hogan, M. Terry
背景资料：使用自行采集的阴道拭子（VS）通过核酸扩增试验（NAAT）检测沙眼衣原体是可以接受的，也是准确的。的目标是实施一个教育的基于互联网的妇女计划，以促进家庭筛查，以确定妇女是否会要求和使用自我收集的VS包，以确定相关的感染风险因素，并确定满意度的process.Methods：该网站，www.iwantthekit.org，旨在鼓励妇女>= 14岁，以获得家庭采样包。可以通过互联网/电子邮件或电话在社区获得工具包。用户将自行收集的VS邮寄到实验室。通过3次NAAT试验检测拭子。结果：四十一400（10.3%）妇女衣原体阳性，95.1%的治疗。调查结果显示，89.5%的人倾向于自行收集，93.5%的人认为收集容易/非常容易，86.3%的人会再次使用互联网程序。黑人种族和年龄< 25岁与衣原体阳性独立相关，而使用避孕措施和非自愿性行为具有保护作用。36/41例（87.8%）3种NAAT均阳性，5/41例（12.2%）仅2种NAAT阳性，0例仅1种NAAT阳性。互联网/电子邮件请求方法优于社区提取方法，因为97.2%的试剂盒请求是通过电子邮件发送的，87.5%的试剂盒返回进行检测是通过电子邮件请求的。
Background: Testing for Chlamydia trachomatis by nucleic acid amplification tests (NAATs) using self-collected vaginal swabs (VS) is acceptable and accurate. The objectives were to implement an educational Internet-based program for women to facilitate home screening, to determine whether women would request and use self-collected VS kits, to determine associated risk factors for infection, and to determine satisfaction with the process.Methods: The website, www.iwantthekit.org, was designed to encourage women >= 14 years to obtain home-sampling kits. Kits could be obtained in the community, requested by Internet/e-mail, or telephone. Users mailed the self-collected VS to the laboratory. Swabs were tested by 3 NAAT assays. Respondents called for results.Results: Forty-one of 400 (10.3%) women were chlamydia positive; 95.1% were treated. Questionnaires indicated 89.5% preferred self-collection, 93.5% rated collection easy/very easy, and 86.3% would use 0the Internet program again. Black race and age < 25 years were associated independently with being chlamydia positive, while use of birth control and nonconsensual sex were protective. Thirty-six of 41 (87.8%) positive samples were positive by all 3 NAATs, 5/41 (12.2%) were positive by only 2 NAATs, and none were positive by only 1 NAAT. The Internet/e-mail request method was better than the community pick-up approach because 97.2 % of kit requests were e-mailed and 87.5% of kits returned for testing were e-mail requested.