Registration-derived estimates of local lung expansion as surrogates for regional ventilation.
Registration-derived estimates of local lung expansion as surrogates for regional ventilation.
复制标题
配准得出的局部肺扩张估计作为区域通气的替代。
DOI：
10.1007/978-3-540-73273-0_63
复制
发表时间：
2007
期刊：
影响因子：
--
通讯作者：
Cao,Kunlin
中科院分区：
文献类型：
--
作者：
Reinhardt,JosephM;Christensen,GaryE;Hoffman,EricA;Ding,Kai;Cao,Kunlin
The main function of the respiratory system is gas exchange. Since many disease or injury conditions can cause biomechanical or material property changes that can alter lung function, there is a great interest in measuring regional lung ventilation. We describe a registration-based technique for estimating local lung expansion from multiple respiratory-gated CT images of the thorax. The degree of regional lung expansion is measured using the Jacobian of the registration displacement field. We compare lung expansion estimated across five pressure changes to a xenon CT based measure of specific ventilation, and have shown good agreement (linear regression,r2= 0.89 during gas wash-in) in one animal.
