Orbital and adnexal lymphomas. A multiparameter approach.
Orbital and adnexal lymphomas. A multiparameter approach.
复制标题
眼眶和附件淋巴瘤。
DOI：
10.1093/ajcp/73.5.615
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发表时间：
1980
影响因子：
3.5
通讯作者：
R. Lukes
中科院分区：
文献类型：
--
作者：
R. Astarita;D. Minckler;C. Taylor;A. Levine;R. Lukes
将免疫、细胞化学和电子显微镜技术应用于眼眶和附件淋巴病变的研究，发现在5例具有挑战性的转诊病例中，提高了恶性淋巴瘤的诊断准确率。尽管仔细的标本采集、理想的固定和处理是结外淋巴瘤形态诊断的基石，但这些淋巴增生性疾病的免疫学特征被强调为一项特别有用的诊断参数。眼眶假性淋巴瘤的假阴性诊断的发生可能部分是由于未能认识到相对常见的浆细胞性淋巴细胞性淋巴瘤，这是一种独特的实体，可能模仿反应性炎症过程。所有报告的恶性淋巴瘤均为I期或II期疾病，提示眼眶原发淋巴瘤可能是一种预后良好的疾病。
The application of immunologic, cytochemical, and electron-microscopic technics to the study of lymphoid lesions of the orbit and adnexa was found to enhance the accuracy of diagnoses of malignant lymphoma in five challenging referral cases. Although careful specimen collection, ideal fixation, and processing constitute the cornerstone of the morphologic diagnosis of nodal and extranodal lymphomas, the immunologic characterization of these lymphoproliferative disorders is emphasized as an especially useful diagnostic parameter. The occurrence of false-negative diagnoses of pseudolymphoma of the orbital region may be partially explained by a failure to recognize the relatively frequent plasma-cytoid lymphocytic lymphoma, a distinctive entity that may mimic a reactive inflammatory process. All of the cases of malignant lymphoma reported represented stage I or stage II disease, suggesting that primary lymphoma of the orbital region may be a disease with a favorable prognosis.