Macrophage-enhanced germination of Bacillus anthracis endospores requires gerS

Macrophage-enhanced germination of Bacillus anthracis endospores requires gerS
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DOI:
10.1128/iai.70.10.5870-5872.2002
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发表时间:
2002-10-01
影响因子:
3.1
通讯作者:
Hanna, PC
Hanna, PC
中科院分区:
医学2区
文献类型:
--
作者:
Ireland, JAW;Hanna, PC

文献摘要

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Germination of Bacillus anthracis Sterne and plasmidless Delta-Sterne endospores was dramatically enhanced in RAW264.7 macrophage-like cells, while germination of nonpathogenic Bacillus endospores was not. Elimination of gerS, a germinant receptor locus, caused a complete loss of cell-enhanced germination, implicating gerS in the breaking of endospore dormancy in vivo.